AJP - Gastrointestinal and Liver Physiology, Vol 238, Issue 2 102-G108, Copyright © 1980 by American Physiological Society
Nervous control of migratory myoelectric complex of the small bowel
P. F. Aeberhard, L. D. Magnenat and W. A. Zimmermann
The effects on the migratory myoelectric complex (MMC) of transplantation
of small bowel loops were investigated in miniature swine with chronically
implanted bipolar electrodes. Four experimental models (A--D) were studied.
In groups A and B, jejunal loops were either interchanged in sequence or
transplanted to the ileum with preservation of intact neurovascular
pedicles. In groups C and D, bowel segments were totally isolated and
replanted in situ (group C) or as modified Thiry-Vella loops (group D).
Weekly records of fasting myoelectrical activity were then taken. Group A
and B animals showed reintegration of the transplanted bowel segments into
a normal MMC sequence after a remodeling period. The replanted bowel
segments of groups C and D displayed MMCs throughout the study period. The
in situ replanted segments of group C were reintegrated into the normal
sequence after a delay of 3--4 wk. These results indicate that the
organization of the MMC is not solely determined by the extrinsic nervous
system.
