AJP - GI AJP: Gastrointestinal and Liver Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Gastrointest Liver Physiol 238: G183-G189, 1980;
0193-1857/80 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Granger, D. N.
Right arrow Articles by Taylor, A. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Granger, D. N.
Right arrow Articles by Taylor, A. E.

AJP - Gastrointestinal and Liver Physiology, Vol 238, Issue 3 183-G189, Copyright © 1980 by American Physiological Society

ARTICLES

Role of the interstitial matrix during intestinal volume absorption

D. N. Granger, N. A. Mortillaro, P. R. Kvietys, G. Rutili, J. C. Parker and A. E. Taylor

The effects of net volume absorption rate (Jv,m) on intestinal interstitial fluid volume (VI), lymph flow (JL), and the excluded volume fraction for interstitial albumin (FE) were analyzed in an autoperfused cat ileum preparation. Tissue blood volume, extracellular space, and extracellular albumin (VA) were estimated using 51Cr-labeled red blood cells, 99mTc-labeled diethylenetriamine pentaacetic acid (DTPA), and 125I-labeled human serum albumin, respectively. Nonabsorptive values of 27.8 ml/100 g, 18.2 ml/100 g, and 0.37 were acquired for VI, VA, and FE, respectively. Net volume absorption results in an increase in intestinal interstitial volume and lymph flow and decreases the degree of albumin exclusion in the interstitial matrix. The magnitude of the changes in interstitial volume, lymph flow, and excluded volume of albumin during net volume absorption are related to the rate of absorption. The increased matrix hydration during absorption serves to enchance vascular and lymphatic removal of absorbed volume.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online