AJP - GI Ad Instruments
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Gastrointest Liver Physiol 239: G95-G98, 1980;
0193-1857/80 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Morisset, J.
Right arrow Articles by Jolicoeur, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Morisset, J.
Right arrow Articles by Jolicoeur, L.

AJP - Gastrointestinal and Liver Physiology, Vol 239, Issue 2 95-G98, Copyright © 1980 by American Physiological Society

ARTICLES

Effect of hydrocortisone on pancreatic growth in rats

J. Morisset and L. Jolicoeur

This study was undertaken to determine the effects of hydrocortisone on pancreatic size and composition in suckling, recently weaned, growing, and adult rats. The data demonstrate that hydrocortisone 1) is associated with hyperplasia and hypertrophy of the pancreas in suckling rats, 2) suppressed DNA synthesis in recently weaned rats, but maintained the hypertrphic effect, 3) increased protein and pancreatic hydrolase concentrations in growing and adult rats, and 4) preferentially promoted synthesis of amylase over chymotrypsin only during the suckling period. These experiments suggest that growth of the pancreas may be partly under control of glucocorticoids only during the suckling period, whereas hypertrophy of the pancreatic tissue can be obtained at all ages by these hormones.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online