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Am J Physiol Gastrointest Liver Physiol 244: G573-G577, 1983;
0193-1857/83 $5.00
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AJP - Gastrointestinal and Liver Physiology, Vol 244, Issue 6 573-G577, Copyright © 1983 by American Physiological Society

ARTICLES

Analyzing tracer disappearance curves to study hepatic transport kinetics

E. L. Forker and B. A. Luxon

This paper is devoted to a discussion of recent developments in the compartmental analysis of hepatic transport, especially the interpretation of tracer disappearance curves recorded from the reservoir of an isolated perfused liver preparation. The emphasis is on the advantages that this approach enjoys over other mathematical models, and a critical review of alternative methods is therefore included. The mathematical equations are largely suppressed, however, having appeared elsewhere in detail.




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