AJP - Gastrointestinal and Liver Physiology, Vol 252, Issue 4 585-G591, Copyright © 1987 by American Physiological Society
Manometry of canine ileocolonic sphincter: comparison of sleeve method to point sensors
E. M. Quigley, J. Dent and S. F. Phillips
Tonic and phasic pressures at the canine ileocolonic sphincter (ICS) were
recorded by a manometric assembly that combined a sleeve sensor with
multiple side-hole pressure ports. By aligning the side holes precisely it
was possible to evaluate in vivo the fidelity of the sleeve relative to
simultaneous pressure records from the point sensors. The ICS exhibited
tonic and phasic pressures, often in excess of 100 cmH2O of pressure. The
sleeve sensor was tolerant of small, but potentially important, movements
of the assembly relative to the ICS. Point sites of recording moved in and
out of the high-pressure zone and side holes were, therefore, not ideal
sensors of sphincteric tone. The anticipated properties of this sleeve,
that it would display reduced fidelity for rapid changes in pressure at
sites away from its point of perfusion, were confirmed in vivo. The sleeve
also "summarized" phasic bursts and was unable to monitor propagation of
such events. However, the combined assembly proved excellent for examining
overall function of the canine ICS.
