| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
AJP - Gastrointestinal and Liver Physiology, Vol 255, Issue 4 490-G497, Copyright © 1988 by American Physiological Society
ARTICLES |
R. Heddle, J. Dent, J. Toouli and N. W. Read
Gastroenterology Unit, Royal Adelaide Hospital, North Terrace, Australia.
The topography of human pyloric pressure is ill defined, and previous studies of pyloric motility in humans have given conflicting results. A detailed profile of pyloric pressure has been recorded in seven healthy volunteers using a manometric assembly with 13 side holes spaced at 3-mm intervals on reverse aspect of a 3.5-cm long sleeve sensor. After a fasting control period of 40 min, recordings were made for 40 min during intraduodenal infusion of a lipid emulsion. Two major patterns of pressure waves were seen during the fasting control period, namely pressure waves confined to a narrow pyloric zone (isolated pyloric pressure waves) and pressure waves that were less localized and involved the antrum and/or duodenum. During lipid infusion the motility pattern was dominated by isolated pyloric pressure waves and localized pyloric tone. Ninety-two percent of the isolated pyloric pressure waves recorded by the sleeve were recorded by only one or two side holes, consistent with a phasically active zone less than 9 mm in length. Pyloric tone was confined to an even narrower zone and was most often recorded by only one side hole. When both tone and isolated pyloric pressure waves occurred together, they were recorded by the same side holes. By comparison with the side holes, the sleeve recorded 89% of isolated pyloric pressure waves and 98% of nonlocalized waves and recorded pyloric tone with a moderate sensitivity but high specificity. The technical challenge of recording localized pyloric contraction is considerable, and much of the conflict between previous studies of the human pylorus is explicable on methodological grounds.(ABSTRACT TRUNCATED AT 250 WORDS)
This article has been cited by other articles:
|
|
 |
|
  K. L Feltrin, T. J Little, J. H Meyer, M. Horowitz, T. Rades, J. Wishart, and C. Feinle-Bisset Comparative effects of intraduodenal infusions of lauric and oleic acids on antropyloroduodenal motility, plasma cholecystokinin and peptide YY, appetite, and energy intake in healthy men Am. J. Clinical Nutrition, May 1, 2008; 87(5): 1181 - 1187. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. J Little, M. Horowitz, and C. Feinle-Bisset Modulation by high-fat diets of gastrointestinal function and hormones associated with the regulation of energy intake: implications for the pathophysiology of obesity Am. J. Clinical Nutrition, September 1, 2007; 86(3): 531 - 541. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. L. Feltrin, T. J. Little, J. H. Meyer, M. Horowitz, T. Rades, J. Wishart, and C. Feinle-Bisset Effects of lauric acid on upper gut motility, plasma cholecystokinin and peptide YY, and energy intake are load, but not concentration, dependent in humans J. Physiol., June 1, 2007; 581(2): 767 - 777. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. J. Little, S. Doran, J. H. Meyer, A. J. P. M. Smout, D. G. O'Donovan, K.-L. Wu, K. L. Jones, J. Wishart, C. K. Rayner, M. Horowitz, et al. The release of GLP-1 and ghrelin, but not GIP and CCK, by glucose is dependent upon the length of small intestine exposed Am J Physiol Endocrinol Metab, September 1, 2006; 291(3): E647 - E655. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. N. Pilichiewicz, T. J. Little, I. M. Brennan, J. H. Meyer, J. M. Wishart, B. Otto, M. Horowitz, and C. Feinle-Bisset Effects of load, and duration, of duodenal lipid on antropyloroduodenal motility, plasma CCK and PYY, and energy intake in healthy men Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2006; 290(3): R668 - R677. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. J. Little, K. L. Feltrin, M. Horowitz, A. J. P. M. Smout, T. Rades, J. H. Meyer, A. N. Pilichiewicz, J. Wishart, and C. Feinle-Bisset Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2005; 289(4): R1090 - R1098. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. M. Brennan, K. L. Feltrin, M. Horowitz, A. J. P. M. Smout, J. H. Meyer, J. Wishart, and C. Feinle-Bisset Evaluation of interactions between CCK and GLP-1 in their effects on appetite, energy intake, and antropyloroduodenal motility in healthy men Am J Physiol Regulatory Integrative Comp Physiol, June 1, 2005; 288(6): R1477 - R1485. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L. Feltrin, T. J. Little, J. H. Meyer, M. Horowitz, A. J. P. M. Smout, J. Wishart, A. N. Pilichiewicz, T. Rades, I. M. Chapman, and C. Feinle-Bisset Effects of intraduodenal fatty acids on appetite, antropyloroduodenal motility, and plasma CCK and GLP-1 in humans vary with their chain length Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2004; 287(3): R524 - R533. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Savoye-Collet, G. Savoye, and A. Smout Determinants of transpyloric fluid transport: a study using combined real-time ultrasound, manometry, and impedance recording Am J Physiol Gastrointest Liver Physiol, December 1, 2003; 285(6): G1147 - G1152. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Feinle, D. O'Donovan, S. Doran, J. M. Andrews, J. Wishart, I. Chapman, and M. Horowitz Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans Am J Physiol Gastrointest Liver Physiol, May 1, 2003; 284(5): G798 - G807. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Savoye, C. Savoye-Collet, J. Oors, and A. J. P. M. Smout Interdigestive transpyloric fluid transport assessed by intraluminal impedance recording Am J Physiol Gastrointest Liver Physiol, April 1, 2003; 284(4): G663 - G669. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Boyd, D. G. O'Donovan, S. Doran, J. Wishart, I. M. Chapman, M. Horowitz, and C. Feinle High-fat diet effects on gut motility, hormone, and appetite responses to duodenal lipid in healthy men Am J Physiol Gastrointest Liver Physiol, February 1, 2003; 284(2): G188 - G196. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Hveem, W. M. Sun, G. Hebbard, M. Horowitz, S. Doran, and J. Dent Relationship between ultrasonically detected phasic antral contractions and antral pressure Am J Physiol Gastrointest Liver Physiol, July 1, 2001; 281(1): G95 - G101. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Indireshkumar, J. G. Brasseur, H. Faas, G. S. Hebbard, P. Kunz, J. Dent, C. Feinle, M. Li, P. Boesiger, M. Fried, et al. Relative contributions of "pressure pump" and "peristaltic pump" to gastric emptying Am J Physiol Gastrointest Liver Physiol, April 1, 2000; 278(4): G604 - G616. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Lingenfelser, W.-M. Sun, G. S. Hebbard, J. Dent, and M. Horowitz Effects of duodenal distension on antropyloroduodenal pressures and perception are modified by hyperglycemia Am J Physiol Gastrointest Liver Physiol, March 1, 1999; 276(3): G711 - G718. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. M. T. Verhagen, M. Samsom, and A. J. P. M. Smout Effects of intraduodenal glucose infusion on gastric myoelectrical activity and antropyloroduodenal motility Am J Physiol Gastrointest Liver Physiol, June 1, 1998; 274(6): G1038 - G1044. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Andrews, S. Doran, G. S. Hebbard, G. Rassias, W.-M. Sun, and M. Horowitz Effect of glucose supplementation on appetite and the pyloric motor response to intraduodenal glucose and lipid Am J Physiol Gastrointest Liver Physiol, April 1, 1998; 274(4): G645 - G652. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
