AJP - GI Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Gastrointest Liver Physiol 257: G30-G40, 1989;
0193-1857/89 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Van Lier Ribbink, J. A.
Right arrow Articles by Tanaka, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Van Lier Ribbink, J. A.
Right arrow Articles by Tanaka, M.

AJP - Gastrointestinal and Liver Physiology, Vol 257, Issue 1 30-G40, Copyright © 1989 by American Physiological Society

ARTICLES

Neural isolation of the entire canine stomach in vivo: effects on motility

J. A. Van Lier Ribbink, M. G. Sarr and M. Tanaka
Department of Surgery, Mayo Medical School, Rochester, Minnesota 55905.

This study was designed to determine the effects of transection of all extrinsic and enteric neural continuity to the entire stomach on motility patterns of the stomach and small intestine. Five dogs were subjected to a model of orthotopic autotransplantation of the stomach to achieve an in vivo, "neurally isolated" stomach. Manometric catheters and serosal electrodes were implanted. A cyclic motor pattern occurred during fasting and was closely coordinated temporally with the migrating motor complex (MMC) in the small bowel. The period of the cyclic gastric motor activity did not differ from the period of the MMC in the small intestine [121 +/- 8 vs 124 +/- 10 (means +/- SE) min, P = 0.4], but the periods of both were greater than in control dogs (93 +/- 5 min, P less than 0.05). Tachygastria accounted for 36 +/- 13% of fasting myoelectric activity in the neurally isolated dogs and for less than 1% in control dogs. Plasma concentration of motilin was greatest during the phase III-like gastric motor activity; exogenous motilin induced premature phase III-like activity in the stomach and small intestine. Feeding abolished the cyclic motor activity in the stomach and decreased plasma motilin concentration. These data suggest that hormonal factors, and not extrinsic or intrinsic neural continuity to the stomach, may control both the initiation of a cyclic interdigestive gastric motor pattern and its temporal coordination with motor patterns in the small intestine.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
J. Huang, H. Zhou, S. Mahavadi, W. Sriwai, V. Lyall, and K. S. Murthy
Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors
Am J Physiol Gastrointest Liver Physiol, January 1, 2005; 288(1): G23 - G31.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
T. Tanaka, M. L. Kendrick, N. J. Zyromski, T. Meile, and M. G. Sarr
Vagal innervation modulates motor pattern but not initiation of canine gastric migrating motor complex
Am J Physiol Gastrointest Liver Physiol, July 1, 2001; 281(1): G283 - G292.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online