AJP - GI Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Gastrointest Liver Physiol 263: G810-G815, 1992;
0193-1857/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Casadevall, M.
Right arrow Articles by Rodes, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Casadevall, M.
Right arrow Articles by Rodes, J.

AJP - Gastrointestinal and Liver Physiology, Vol 263, Issue 5 810-G815, Copyright © 1992 by American Physiological Society

ARTICLES

Limitations of laser-Doppler velocimetry and reflectance spectrophotometry in estimating gastric mucosal blood flow

M. Casadevall, J. Panes, J. M. Pique, J. Bosch, J. Teres and J. Rodes
Gastroenterology Department, Hospital Clinic, University of Barcelona, Spain.

This study investigated the accuracy of laser-Doppler flowmetry (LDV) and reflectance spectrophotometry (RS) measurements as an index of blood flow in the gastric mucosa of the rat, in experimental conditions such as pharmacologically induced vasoconstriction, hypoxia, hyperoxia, and acute normovolemic anemia. Hydrogen gas clearance was used as a reference method. After vasopressin infusion, LDV signal and indexes of hemoglobin (IHb) and oxygen (ISO2) content in the gastric mucosa estimated by RS significantly decreased in parallel with the reduction of gastric mucosal blood flow (GMBF). Neither hypoxia (5% O2 administration) nor hyperoxia (100% O2) affected GMBF or LDV signal. However, both IHb and ISO2 significantly decreased or increased after hypoxia or hyperoxia, respectively. Acute normovolemic anemia induced a significant increase in GMBF, while LDV signal and ISO2 remained unchanged. IHb significantly decreased in linear relationship with the decrements in the hematocrit. It is concluded that 1) in pharmacologically induced GMBF changes, LDV and RS correlate with GMBF; 2) when changes in hemoglobin saturation are induced, LDV but not RS reflects GMBF; and 3) in acute normovolemic anemia, neither LDV nor RS reflects changes in GMBF.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
H. Kaneko, J. Kaunitz, and Y. Tache
Vagal mechanisms underlying gastric protection induced by chemical activation of raphe pallidus in rats
Am J Physiol Gastrointest Liver Physiol, November 1, 1998; 275(5): G1056 - G1062.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
B. TEMMESFELD-WOLLBRÜCK, A. SZALAY, K. MAYER, H. OLSCHEWSKI, W. SEEGER, and F. GRIMMINGER
Abnormalities of Gastric Mucosal Oxygenation in Septic Shock . Partial Responsiveness to Dopexamine
Am. J. Respir. Crit. Care Med., May 1, 1997; 157(5): 1586 - 1592.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online