AJP - Gastrointestinal and Liver Physiology, Vol 265, Issue 4 646-G653, Copyright © 1993 by American Physiological Society
Gastric myoelectric and motor activity in dogs with gastric dilatation-volvulus
J. A. Hall, T. N. Solie, H. B. Seim 3rd and D. C. Twedt
Department of Physiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
Electrical and contractile properties of the stomach were assessed in six
adult dogs after recovery from surgical treatment for gastric
dilatation-volvulus (GDV), a disorder characterized by delayed gastric
emptying of the solid phase. Electrodes and strain-gauge force transducers
were sutured to the serosa of the antrum and pylorus at the time of
surgical intervention for GDV. Ten days after implantation, electrical and
mechanical activities were recorded before and after a standardized meal.
The analog FM tape recordings of the electrical and mechanical signals were
converted to digital time series for analysis by computer. Recordings from
dogs after GDV showed increased slow wave propagation velocity in both the
fasting and the fed states compared with controls. In addition, the GDV
dogs had atypical fasting state phase III activity fronts. We found no
difference in gastric slow wave frequency, dysrhythmia, or
electromechanical coupling between the two groups. These results indicate
that delayed gastric emptying in this syndrome is associated with increased
gastric slow wave propagation velocity.
