AJP - Gastrointestinal and Liver Physiology, Vol 266, Issue 1 90-G98, Copyright © 1994 by American Physiological Society

ARTICLES

Serosal and cutaneous recordings of gastric myoelectrical activity in patients with gastroparesis

J. D. Chen, B. D. Schirmer and R. W. McCallum
Department of Internal Medicine, University of Virginia Health Science Center, Charlottesville 22908.

The aims of this study were to 1) investigate gastric myoelectrical activity in patients with gastroparesis, 2) validate the cutaneous electrogastrogram (EGG) in tracking the frequency change of the gastric slow wave, and 3) investigate the effect of electrical stimulation on gastric myoelectrical activity. Gastric myoelectrical activity was recorded in 12 patients with documented gastroparesis using serosal electrodes for > 200 min in each subject. All recordings were made at least 4 days after surgery. Each session consisted of a 30-min recording in the fasting state and a 30-min recording after a test meal. The test meal (liquid or mixed) was selected according to patient's tolerance. Electrical stimulation was performed in three subjects via the serosal electrodes at a frequency of 3 cycles/min. Gastric myoelectrical activity was recorded using serosal electrodes in each session. The serosal recording showed slow waves of 2.5 to 4.0 cycles/min in all 12 subjects. Absence of spikes was noted in 11 of the 12 subjects. The simultaneous serosal and cutaneous recording of gastric myoelectrical activity showed that the frequency of the EGG was exactly the same as that of the serosal recording. Liquid meals resulted in a significant decrease in slow-wave frequency (Student's t test, P = 0.006), and the EGG accurately reflected this change. Electrical stimulation had no effect on the frequency of the gastric slow wave and did not induce spikes.(ABSTRACT TRUNCATED AT 250 WORDS)

This article has been cited by other articles:

				X. Lin and J. Z. Chen Abnormal gastric slow waves in patients with functional dyspepsia assessed by multichannel electrogastrography Am J Physiol Gastrointest Liver Physiol, June 1, 2001; 280(6): G1370 - G1375. [Abstract] [Full Text] [PDF]

				J. D. Z. Chen, X. Zou, X. Lin, S. Ouyang, and J. Liang Detection of gastric slow wave propagation from the cutaneous electrogastrogram Am J Physiol Gastrointest Liver Physiol, August 1, 1999; 277(2): G424 - G430. [Abstract] [Full Text] [PDF]

				J. Liang, E. Co, M. Zhang, J. Pineda, and J. D. Z. Chen Development of gastric slow waves in preterm infants measured by electrogastrography Am J Physiol Gastrointest Liver Physiol, March 1, 1998; 274(3): G503 - G508. [Abstract] [Full Text] [PDF]

				Z. Y. Lin, R. W. McCallum, B. D. Schirmer, and J. D. Z. Chen Effects of pacing parameters on entrainment of gastric slow waves in patients with gastroparesis Am J Physiol Gastrointest Liver Physiol, January 1, 1998; 274(1): G186 - G191. [Abstract] [Full Text] [PDF]