| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
AJP - Gastrointestinal and Liver Physiology, Vol 270, Issue 1 1-G5, Copyright © 1996 by American Physiological Society
ARTICLES |
J. L. Boyer
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
The bile duct epithelium is known to modify hepatic bile by both secretory and absorptive processes. However, identification and characterization of the transport systems that carry out these physiological functions at the cellular and molecular level have been slow compared with progress in understanding hepatic bile production. Recently, techniques have been developed that enable bile duct cells to be isolated in substantial number and purity and as intact polarized units that can be studied in vitro. These newer preparations have enabled classic physiological approaches to be performed directly with the bile duct epithelial tissues. Progress in this important area of biliary physiology is now rapid and forms the basis for this review.
This article has been cited by other articles:
|
|
 |
|
  N. Abuladze, A. Pushkin, S. Tatishchev, D. Newman, P. Sassani, and I. Kurtz Expression and localization of rat NBC4c in liver and renal uroepithelium Am J Physiol Cell Physiol, September 1, 2004; 287(3): C781 - C789. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Alpini, J. L. Phinizy, S. Glaser, H. Francis, A. Benedetti, L. Marucci, and G. LeSage Development and characterization of secretin-stimulated secretion of cultured rat cholangiocytes Am J Physiol Gastrointest Liver Physiol, June 1, 2003; 284(6): G1066 - G1073. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A.-Y. Gong, P. S. Tietz, M. A. Muff, P. L. Splinter, R. C. Huebert, M. Z. Strowski, X.-M. Chen, and N. F. LaRusso Somatostatin stimulates ductal bile absorption and inhibits ductal bile secretion in mice via SSTR2 on cholangiocytes Am J Physiol Cell Physiol, May 1, 2003; 284(5): C1205 - C1214. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Trauner and J. L. Boyer Bile Salt Transporters: Molecular Characterization, Function, and Regulation Physiol Rev, April 1, 2003; 83(2): 633 - 671. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. A. Choate, K. T. Kahle, F. H. Wilson, C. Nelson-Williams, and R. P. Lifton WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl--transporting epithelia PNAS, January 21, 2003; 100(2): 663 - 668. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Mennone, A. S. Verkman, and J. L. Boyer Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice Am J Physiol Gastrointest Liver Physiol, September 1, 2002; 283(3): G739 - G746. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A.-Y. Gong, A. I. Masyuk, P. L. Splinter, R. C. Huebert, P. S. Tietz, and N. F. LaRusso Channel-mediated water movement across enclosed or perfused mouse intrahepatic bile duct units Am J Physiol Cell Physiol, July 1, 2002; 283(1): C338 - C346. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Kanno, G. LeSage, S. Glaser, and G. Alpini Regulation of cholangiocyte bicarbonate secretion Am J Physiol Gastrointest Liver Physiol, September 1, 2001; 281(3): G612 - G625. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. K. Singh, A. Mennone, A. Gigliozzi, F. Fraioli, and J. L. Boyer Cl{-}-dependent secretory mechanisms in isolated rat bile duct epithelial units Am J Physiol Gastrointest Liver Physiol, August 1, 2001; 281(2): G438 - G446. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. K. Cho, A. Mennone, and J. L. Boyer Isolation of functional polarized bile duct units from mouse liver Am J Physiol Gastrointest Liver Physiol, February 1, 2001; 280(2): G241 - G246. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Mennone, D. Biemesderfer, D. Negoianu, C.-L. Yang, T. Abbiati, P. J. Schultheis, G. E. Shull, P. S. Aronson, and J. L. Boyer Role of sodium/hydrogen exchanger isoform NHE3 in fluid secretion and absorption in mouse and rat cholangiocytes Am J Physiol Gastrointest Liver Physiol, February 1, 2001; 280(2): G247 - G254. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Akaiwa, Y. Yae, R. Sugimoto, S. O. Suzuki, T. Iwaki, K. Izuhara, and N. Hamasaki Hakata Antigen, a New Member of the Ficolin/Opsonin p35 Family, Is a Novel Human Lectin Secreted into Bronchus/Alveolus and Bile J. Histochem. Cytochem., June 1, 1999; 47(6): 777 - 786. [Abstract] [Full Text]
|
|
|
|
|
|
R. A. Marinelli, P. S. Tietz, L. D. Pham, L. Rueckert, P. Agre, and N. F. LaRusso Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes Am J Physiol Gastrointest Liver Physiol, January 1, 1999; 276(1): G280 - G286. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Trauner, P. J. Meier, and J. L. Boyer Molecular Pathogenesis of Cholestasis N. Engl. J. Med., October 22, 1998; 339(17): 1217 - 1227. [Full Text] [PDF]
|
|
|
|
 |
|
 R. A. Marinelli, L. Pham, P. Agre, and N. F. LaRusso Secretin Promotes Osmotic Water Transport in Rat Cholangiocytes by Increasing Aquaporin-1 Water Channels in Plasma Membrane. EVIDENCE FOR A SECRETIN-INDUCED VESICULAR TRANSLOCATION OF AQUAPORIN-1 J. Biol. Chem., May 16, 1997; 272(20): 12984 - 12988. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
