AJP - GI Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Gastrointest Liver Physiol 279: G1-G6, 2000;
0193-1857/00 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (18)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ladabaum, U.
Right arrow Articles by Owyang, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ladabaum, U.
Right arrow Articles by Owyang, C.
Vol. 279, Issue 1, G1-G6, July 2000

THEME
Pathobiology of Visceral Pain: Molecular Mechanisms and Therapeutic Implications V. Central nervous system processing of somatic and visceral sensory signals

Uri Ladabaum1, Satoshi Minoshima2, and Chung Owyang3

1 Division of Gastroenterology, Department of Medicine, University of California, San Francisco, California 94143-0538; and Divisions of 2 Nuclear Medicine and 3 Gastroenterology, Department of Medicine, University of Michigan, Ann Arbor, Michigan 48109-0362

Somatic and visceral sensation, including pain perception, can be studied noninvasively in humans with functional brain imaging techniques. Positron emission tomography and functional magnetic resonance imaging have identified a series of cerebral regions involved in the processing of somatic pain, including the anterior cingulate, insular, prefrontal, inferior parietal, primary and secondary somatosensory, and primary motor and premotor cortices, the thalamus, hypothalamus, brain stem, and cerebellum. Experimental evidence supports possible specific roles for individual structures in processing the various dimensions of pain, such as encoding of affect in the anterior cingulate cortex. Visceral sensation has been examined in the setting of myocardial ischemia, distension of hollow viscera, and esophageal acidification. Although knowledge regarding somatic sensation is more extensive than the information available for visceral sensation, important similarities have emerged between cerebral representations of somatic and visceral pain.

positron emission tomography; functional magnetic resonance imaging; pain; brain; perception


This article has been cited by other articles:


Home page
 Adv. Psychiatr. Treat.Home page
S. A. Spence
All in the mind? The neural correlates of unexplained physical symptoms
Advan. Psychiatr. Treat., September 1, 2006; 12(5): 349 - 358.
[Abstract] [Full Text] [PDF]

Home page
 GutHome page
A M Drewes, S A K Sami, G Dimcevski, K D Nielsen, P Funch-Jensen, M Valeriani, and L Arendt-Nielsen
Cerebral processing of painful oesophageal stimulation: a study based on independent component analysis of the EEG
Gut, May 1, 2006; 55(5): 619 - 629.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online