HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) All Versions of this Article: 286/2/G263    most recent 00228.2003v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (9) Citing Articles via Google Scholar Google Scholar Articles by Imam, H. Articles by Soffer, E. Search for Related Content PubMed PubMed Citation Articles by Imam, H. Articles by Soffer, E.

NEUROREGULATION AND MOTILITY

Study of intestinal flow by combined videofluoroscopy, manometry, and multiple intraluminal impedance

Departments of ¹Gastroenterology and Hepatology, ²Biostatistics, and ³Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195

Submitted 16 May 2003 ; accepted in final form 12 September 2003

Assessment of patterns of flow in the small bowel is difficult. Multiple intraluminal impedance has been recently used for study of flow dynamics in the esophagus. Our aims were 1) to validate multiple intraluminal impedance by correlating impedance events with intestinal flow as detected by fluoroscopy and 2) to determine intestinal flow patterns in the fasting and postprandial period and their correspondence with manometry. First, six healthy subjects underwent simultaneous video-fluoroscopic, manometric, and impedance recording from the duodenum. Videofluoroscopy was used to validate impedance patterns corresponding with barium flow in the fasting and postprandial periods. Next, 16 healthy subjects underwent prolonged simultaneous recording of impedance and manometry in both periods. Most flow events were short (10 cm or less), with antegrade flow being the most common. Correspondence between impedance and videofluoroscopy increased with increasing length of barium flow. Impedance corresponded better with flow, at any distance, than manometry. However, impedance and manometric events, when analyzed separately as index events, always corresponded with fluoroscopic flow. The fasting and postprandial periods showed comparable patterns of flow, with frequent, highly propulsive manometric and impedance sequences. Motility index was positively and significantly associated with length of impedance events. Phase 3 of the migrating motor complex could be easily recognized by impedance. Multiple intraluminal impedance can detect intestinal flow events and corresponds better with fluoroscopic flow than manometry.

multichannel intraluminal impedance; manometry; fluoroscopy; intestinal motility

This article has been cited by other articles:

				R. Chaikomin, K. L. Wu, S. Doran, K. L. Jones, A. J. P. M. Smout, W. Renooij, R. H. Holloway, J. H. Meyer, M. Horowitz, and C. K. Rayner Concurrent duodenal manometric and impedance recording to evaluate the effects of hyoscine on motility and flow events, glucose absorption, and incretin release Am J Physiol Gastrointest Liver Physiol, April 1, 2007; 292(4): G1099 - G1104. [Abstract] [Full Text] [PDF]