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This Article Full Text Full Text (PDF) All Versions of this Article: 287/2/G459    most recent 00323.2003v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Web of Science (8) Citing Articles via Google Scholar Google Scholar Articles by Satow, T. Articles by Shibasaki, H. Search for Related Content PubMed PubMed Citation Articles by Satow, T. Articles by Shibasaki, H.

NEUROREGULATION AND MOTILITY

Role of primary sensorimotor cortex and supplementary motor area in volitional swallowing: a movement-related cortical potential study

¹Human Brain Research Center, ²Departments of Neurosurgery, and ³Neurology, Kyoto University Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto 606-8507; ⁴The National Epilepsy Center, Shizuoka Medical Institute for Neurological Disorders, Urushiyama, Shizuoka 420-0953, Japan; and ⁵National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-1428

Submitted 30 July 2003 ; accepted in final form 23 December 2003

We investigated the role of the cerebral cortex, particularly the face/tongue area of the primary sensorimotor (SMI) cortex (face/tongue) and supplementary motor area (SMA), in volitional swallowing by recording movement-related cortical potentials (MRCPs). MRCPs with swallowing and tongue protrusion were recorded from scalp electrodes in eight normal right-handed subjects and from implanted subdural electrodes in six epilepsy patients. The experiment by scalp EEG in normal subjects revealed that premovement Bereitschaftspotentials (BP) activity for swallowing was largest at the vertex and lateralized to either hemisphere in the central area. The experiment by epicortical EEG in patients confirmed that face/tongue SMI and SMA were commonly involved in swallowing and tongue protrusion with overlapping distribution and interindividual variability. BP amplitude showed no difference between swallowing and tongue movements, either at face/tongue SMI or at SMA, whereas postmovement potential (PMP) was significantly larger in tongue protrusion than in swallowing only at face/tongue SMI. BP occurred earlier in swallowing than in tongue protrusion. Comparison between face/tongue SMI and SMA did not show any difference with regard to BP and PMP amplitude or BP onset time in either task. The preparatory role of the cerebral cortex in swallowing was similar to that in tongue movement, except for earlier activation in swallowing. Postmovement processing of swallowing was lesser than that of tongue movement in face/tongue SMI; probably suggesting that the cerebral cortex does not play a significant role in postmovement processing of swallowing. SMA plays a supplementary role to face/tongue SMI both in swallowing and tongue movements.

deglutition; electrophysiology; human