AJP - GI Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Am J Physiol Gastrointest Liver Physiol (December 6, 2007). doi:10.1152/ajpgi.00167.2007
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
294/2/G391    most recent
00167.2007v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (8)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Elvevold, K.
Right arrow Articles by Martinez, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Elvevold, K.
Right arrow Articles by Martinez, I.
Submitted on April 16, 2007
Accepted on November 30, 2007

THE LIVER SINUSOIDAL ENDOTHELIAL CELL: A CELL TYPE OF CONTROVERSIAL AND CONFUSING IDENTITY

Kjetil Elvevold1, Bard Smedsrod1*, and Inigo Martinez2

1 Dept of Cell Biology and Histology, University of Tromso, Norway
2 Dept of Orthopaedic Surgery, University of Tromso, Norway

* To whom correspondence should be addressed. E-mail: baards{at}fagmed.uit.no.

A look through the literature on liver endothelial cells (LSECs) reveals that there are several conflicts among different authors of what this cell type is and does. Major controversies that will be highlighted in this review include aspects of the physiological role, the characterization, and the protocols of isolation and cultivation of these cells. Many of these conflicts may be ascribed to the fact that the cell was only recently established as a distinct cell type, and that researchers from different disciplines tend to define their structure and function differently. This field is in need of a common platform to obtain a sound communication and a unified understanding of how to interpret novel research results. The aim of this review is to encourage scientists not to ignore the fact that there are indeed different opinions in the literature on LSECs. We also hope that this review will point out to the reader that some issues that may seem well established regarding our knowledge about the LSECs, in reality are still unresolved and indeed controversial.




This article has been cited by other articles:


Home page
 J. Virol.Home page
C. K. Seckert, A. Renzaho, H.-M. Tervo, C. Krause, P. Deegen, B. Kuhnapfel, M. J. Reddehase, and N. K. A. Grzimek
Liver Sinusoidal Endothelial Cells Are a Site of Murine Cytomegalovirus Latency and Reactivation
J. Virol., September 1, 2009; 83(17): 8869 - 8884.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
S. C. Satchell and F. Braet
Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier
Am J Physiol Renal Physiol, May 1, 2009; 296(5): F947 - F956.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
A. C. Straub, L. R. Klei, D. B. Stolz, and A. Barchowsky
Arsenic Requires Sphingosine-1-Phosphate Type 1 Receptors to Induce Angiogenic Genes and Endothelial Cell Remodeling
Am. J. Pathol., May 1, 2009; 174(5): 1949 - 1958.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
V. C. Cogger, I. M. Arias, A. Warren, A. C. McMahon, D. L. Kiss, V. M. Avery, and D. G. Le Couteur
The response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells
Am J Physiol Gastrointest Liver Physiol, July 1, 2008; 295(1): G137 - G145.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 1977 by the American Physiological Society.