| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Articles in PresS, published online ahead of print July 31, 2002
Am J Physiol Gastrointest Liver Physiol, 10.1152/ajpgi.00249.2002
Submitted on June 27, 2002
Accepted on July 16, 2002
1 Department of Psychological Sciences, Purdue University, West Lafayette, IN, USA
* To whom correspondence should be addressed. E-mail: rphillip{at}psych.purdue.edu.
An understanding of the events initiating vago-vagal reflexes requires knowledge of mechanisms of transduction by vagal afferents. Such information presumes an understanding of receptor morphology and location. Anatomical studies have recently characterized two types of vagal afferents, both putative mechanoreceptors distributed in gastrointestinal (GI) smooth muscle. These two receptors are highly specialized in that they (1) are morphologically distinct, (2) have different smooth muscle targets, (3) complex with dissimilar accessory cells, and (4) vary in their regional distributions throughout the GI tract. By comparison, information on the architecture and regional distributions of other classes of vagal afferents, notably chemoreceptors, has only begun to accumulate. The progress on the two mechanoreceptors, however, illustrates general principles and delineates experimental issues that may apply to other submodalities of vagal afferents. By extension from morphological and physiological observations on the two species of smooth muscle endings, it is reasonable to hypothesize that additional classes of vagal receptors are also differentiated morphologically and that they vary in structure, accessory cells, regional distributions, and other features. A full appreciation of vago-vagal reflexes will require thorough structural and regional analyses of each of the types of vagal receptors within the GI tract.
This article has been cited by other articles:
|
|
 |
|
  P. R. Wade and P. J. Hornby Age-Related Neurodegenerative Changes and How They Affect the Gut Sci. Aging Knowl. Environ., March 23, 2005; 2005(12): pe8 - pe8. [Abstract] [Full Text]
|
|
|
|
 |
|
 Y. M. Kang, K. Lamb, G. F. Gebhart, and K. Bielefeldt Experimentally induced ulcers and gastric sensory-motor function in rats Am J Physiol Gastrointest Liver Physiol, February 1, 2005; 288(2): G284 - G291. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. E. Raybould The Future of GI and Liver Research: Editorial Perspectives: IV. Visceral afferents: an update Am J Physiol Gastrointest Liver Physiol, June 1, 2003; 284(6): G880 - G882. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. N. Browning and D. Mendelowitz Musings on the Wanderer: What's New in Our Understanding of Vago-Vagal Reflexes?: II. Integration of afferent signaling from the viscera by the nodose ganglia Am J Physiol Gastrointest Liver Physiol, January 1, 2003; 284(1): G8 - G14. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| Visit Other APS Journals Online |
