Vol. 283, Issue 4, G827-G832, October 2002
THEME
Aging and Neural Control of the GI Tract
II. Neural control
of the aging gut: can an old dog learn new tricks?
Karen E.
Hall
Geriatric Research, Education, and Clinical Center, Ann
Arbor Veterans Affairs Healthcare System, Ann Arbor 48105; and
Department of Internal Medicine, University of Michigan, Ann Arbor,
Michigan 48109
There has been a dramatic increase
in funding available for aging research, primarily due to the fact that
answers to questions on aging are likely to have a major impact on the
well-being and healthy aging of the world's population for decades to
come. The incidence of certain gastrointestinal problems, such as
dysphagia and constipation, increases dramatically with age. Changes in gastrointestinal neuromuscular function with aging have been
demonstrated in both human and animal models of aging. This article
focuses on recent advances in our knowledge of the effects of aging on gastrointestinal function, treatment options, and future opportunities for research.
aging myentene; dysphagia; constipation; neuronal
dysfunction