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Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

Yasunari Asano, Tetsuya Hiramoto, Ryo Nishino, Yuji Aiba, Tae Kimura, Kazufumi Yoshihara, Yasuhiro Koga, Nobuyuki Sudo
American Journal of Physiology - Gastrointestinal and Liver Physiology Published 1 December 2012 Vol. 303 no. 11, G1288-G1295 DOI: 10.1152/ajpgi.00341.2012
Yasunari Asano
1Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;
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Tetsuya Hiramoto
1Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;
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Ryo Nishino
2Department of Infectious Diseases, Tokai University of Medicine, Isehara, Japan; and
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Yuji Aiba
2Department of Infectious Diseases, Tokai University of Medicine, Isehara, Japan; and
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Tae Kimura
1Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;
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Kazufumi Yoshihara
1Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; 3Department of Cerebral Research, Division of Cerebral Integration, National Institute for Physiological Sciences, Okazaki, Japan
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Yasuhiro Koga
2Department of Infectious Diseases, Tokai University of Medicine, Isehara, Japan; and
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Nobuyuki Sudo
1Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;
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Article Information

vol. 303 no. 11 G1288-G1295
DOI 
https://doi.org/10.1152/ajpgi.00341.2012
PubMed 
23064760
Published By 
American Physiological Society
Print ISSN 
0193-1857
Online ISSN 
1522-1547
History 
  • Submitted August 30, 2012
  • Accepted October 8, 2012
Copyright & Usage 
Copyright © 2012 the American Physiological Society

other Versions

  • previous version (Thursday, October 11, 2012 - 11:55 AM).
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Author Information

  1. Yasunari Asano1,
  2. Tetsuya Hiramoto1,
  3. Ryo Nishino2,
  4. Yuji Aiba2,
  5. Tae Kimura1,
  6. Kazufumi Yoshihara1,3,
  7. Yasuhiro Koga2, and
  8. Nobuyuki Sudo1
  1. 1Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;
  2. 2Department of Infectious Diseases, Tokai University of Medicine, Isehara, Japan; and
  3. 3Department of Cerebral Research, Division of Cerebral Integration, National Institute for Physiological Sciences, Okazaki, Japan
  1. Address for reprint requests and other correspondence: N. Sudo, Dept. of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu Univ., 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan (e-mail: nobuyuki{at}med.kyushu-u.ac.jp).
  • Submitted 30 August 2012.
  • Accepted 8 October 2012.
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Keywords

β-glucuronidase
catecholamines
gut microbiota
germfree
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Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice
Yasunari Asano, Tetsuya Hiramoto, Ryo Nishino, Yuji Aiba, Tae Kimura, Kazufumi Yoshihara, Yasuhiro Koga, Nobuyuki Sudo
American Journal of Physiology - Gastrointestinal and Liver Physiology Dec 2012, 303 (11) G1288-G1295; DOI: 10.1152/ajpgi.00341.2012

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Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice
Yasunari Asano, Tetsuya Hiramoto, Ryo Nishino, Yuji Aiba, Tae Kimura, Kazufumi Yoshihara, Yasuhiro Koga, Nobuyuki Sudo
American Journal of Physiology - Gastrointestinal and Liver Physiology Dec 2012, 303 (11) G1288-G1295; DOI: 10.1152/ajpgi.00341.2012
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American Journal of Physiology - Gastrointestinal and Liver Physiology® and the APS® logo are registered trademarks of the American Physiological Society | Print ISSN: 0193-1857 | Online ISSN: 1522-1547