Bianco and colleagues show that prucalopride is an effective neuroprotective agent against oxidative stress. This work extends prior observations on 5-HT4-mediated neuroprotection and shows that a new treatment modality may soon be tested for efficacy against inflammatory bowel disease and neurodegenenerative disorders of the enteric nervous system.
- enteric nervous system
- 5-HT4 receptor
- oxidative stress
- Copyright © 2016, American Journal of Physiology- Gastrointestinal and Liver Physiology