THEMES:

Min You and David W. Crabb

Recent Advances in Alcoholic Liver Disease II. Minireview: molecular mechanisms of alcoholic fatty liver
Am J Physiol Gastrointest Liver Physiol 287: G1-G6, 2004; 10.1152/ajpgi.00056.2004 [Abstract] [Full Text] [PDF]  

Steven H. Itzkowitz and Xianyang Yio

Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation
Am J Physiol Gastrointest Liver Physiol 287: G7-G17, 2004; 10.1152/ajpgi.00079.2004 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Fabio Marra, Wanda Delogu, Ilaria Petrai, Sabrina Pastacaldi, Andrea Bonacchi, Eva Efsen, Sara Aleffi, Cristiana Bertolani, Massimo Pinzani, and Paolo Gentilini

Differential requirement of members of the MAPK family for CCL2 expression by hepatic stellate cells
Am J Physiol Gastrointest Liver Physiol 287: G18-G26, 2004. First published March 11, 2004; 10.1152/ajpgi.00336.2003 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Matthew E. Loewen, Lane K. Bekar, Wolfgang Walz, George W. Forsyth, and Sherif E. Gabriel

pCLCA1 lacks inherent chloride channel activity in an epithelial colon carcinoma cell line
Am J Physiol Gastrointest Liver Physiol 287: G33-G41, 2004. First published February 26, 2004; 10.1152/ajpgi.00023.2004 [Abstract] [Full Text] [PDF]  

Donnie E. Shifflett, Frank G. Bottone, Jr., Karen M. Young, Adam J. Moeser, Samuel L. Jones, and Anthony T. Blikslager

Neutrophils augment recovery of porcine ischemia-injured ileal mucosa by an IL-1- and COX-2-dependent mechanism
Am J Physiol Gastrointest Liver Physiol 287: G50-G57, 2004. First published March 11, 2004; 10.1152/ajpgi.00076.2003 [Abstract] [Full Text] [PDF]  

Masako Aoi, Eitaro Aihara, Masato Nakashima, and Koji Takeuchi

Participation of prostaglandin E receptor EP4 subtype in duodenal bicarbonate secretion in rats
Am J Physiol Gastrointest Liver Physiol 287: G96-G103, 2004; 10.1152/ajpgi.00038.2004 [Abstract] [Full Text] [PDF]  

Matthew S. Keller, Toshihiko Ezaki, Rong-Jun Guo, and John P. Lynch

Cdx1 or Cdx2 expression activates E-cadherin-mediated cell-cell adhesion and compaction in human COLO 205 cells
Am J Physiol Gastrointest Liver Physiol 287: G104-G114, 2004. First published February 19, 2004; 10.1152/ajpgi.00484.2003 [Abstract] [Full Text] [PDF]  

O. Bachmann, B. Riederer, H. Rossmann, S. Groos, P. J. Schultheis, G. E. Shull, M. Gregor, M. P. Manns, and U. Seidler

The Na⁺/H⁺ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation
Am J Physiol Gastrointest Liver Physiol 287: G125-G133, 2004. First published February 12, 2004; 10.1152/ajpgi.00332.2003 [Abstract] [Full Text] [PDF]  

M. Palmada, M. Dieter, A. Speil, C. Böhmer, A. F. Mack, H. J. Wagner, K. Klingel, R. Kandolf, H. Murer, J. Biber, E. I. Closs, and F. Lang

Regulation of intestinal phosphate cotransporter NaPi IIb by ubiquitin ligase Nedd4–2 and by serum- and glucocorticoid-dependent kinase 1
Am J Physiol Gastrointest Liver Physiol 287: G143-G150, 2004. First published March 25, 2004; 10.1152/ajpgi.00121.2003 [Abstract] [Full Text] [PDF]  

Veronika Gresz, Tae-Hwan Kwon, Hong Gong, Peter Agre, Martin C. Steward, Landon S. King, and Søren Nielsen

Immunolocalization of AQP-5 in rat parotid and submandibular salivary glands after stimulation or inhibition of secretion in vivo
Am J Physiol Gastrointest Liver Physiol 287: G151-G161, 2004. First published February 26, 2004; 10.1152/ajpgi.00480.2003 [Abstract] [Full Text] [PDF]  

Qiang Li, Andrei Manolescu, Mabel Ritzel, Sylvia Yao, Melissa Slugoski, James D. Young, Xing-Zhen Chen, and Chris I. Cheeseman

Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine
Am J Physiol Gastrointest Liver Physiol 287: G236-G242, 2004. First published March 19, 2004; 10.1152/ajpgi.00396.2003 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

Matthew J. DiMagno, John A. Williams, Yibai Hao, Stephen A. Ernst, and Chung Owyang

Endothelial nitric oxide synthase is protective in the initiation of caerulein-induced acute pancreatitis in mice
Am J Physiol Gastrointest Liver Physiol 287: G80-G87, 2004. First published February 12, 2004; 10.1152/ajpgi.00525.2003 [Abstract] [Full Text] [PDF]  

Emile M. Rijcken, Mike G. Laukoetter, Christoph Anthoni, Stephanie Meier, Rudolf Mennigen, Hans-Ullrich Spiegel, Matthias Bruewer, Norbert Senninger, Dietmar Vestweber, and Christian F. Krieglstein

Immunoblockade of PSGL-1 attenuates established experimental murine colitis by reduction of leukocyte rolling
Am J Physiol Gastrointest Liver Physiol 287: G115-G124, 2004. First published March 4, 2004; 10.1152/ajpgi.00207.2003 [Abstract] [Full Text] [PDF]  

José-Antonio Gómez, Xavier Molero, Eva Vaquero, Ana Alonso, Antonio Salas, and Juan-R. Malagelada

Vitamin E attenuates biochemical and morphological features associated with development of chronic pancreatitis
Am J Physiol Gastrointest Liver Physiol 287: G162-G169, 2004. First published March 4, 2004; 10.1152/ajpgi.00333.2003 [Abstract] [Full Text] [PDF]  

F. De Jonge, A. De Laet, L. Van Nassauw, J. K. Brown, H. R. P. Miller, P.-P. van Bogaert, J.-P. Timmermans, and A. B. A. Kroese

In vitro activation of murine DRG neurons by CGRP-mediated mucosal mast cell degranulation
Am J Physiol Gastrointest Liver Physiol 287: G178-G191, 2004. First published March 11, 2004; 10.1152/ajpgi.00528.2003 [Abstract] [Full Text] [PDF]  

Gisela Sparmann, Christine Hohenadl, Jens Tornøe, Robert Jaster, Brit Fitzner, Dirk Koczan, Hans-Jürgen Thiesen, Änne Glass, David Winder, Stefan Liebe, and Jörg Emmrich

Generation and characterization of immortalized rat pancreatic stellate cells
Am J Physiol Gastrointest Liver Physiol 287: G211-G219, 2004. First published February 19, 2004; 10.1152/ajpgi.00347.2003 [Abstract] [Full Text] [PDF]  

Jun Sun, Michael E. Hobert, Anjali S. Rao, Andrew S. Neish, and James L. Madara

Bacterial activation of -catenin signaling in human epithelia
Am J Physiol Gastrointest Liver Physiol 287: G220-G227, 2004. First published February 5, 2004; 10.1152/ajpgi.00498.2003 [Abstract] [Full Text] [PDF]  

Hedy H. Ginzberg, Patrick T. Shannon, Tomoko Suzuki, Ouyang Hong, Eric Vachon, Theo Moraes, Maria Teresa Herrera Abreu, Vera Cherepanov, Xiaomin Wang, Chung-Wai Chow, and Gregory P. Downey

Leukocyte elastase induces epithelial apoptosis: role of mitochondial permeability changes and Akt
Am J Physiol Gastrointest Liver Physiol 287: G286-G298, 2004; 10.1152/ajpgi.00350.2003 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Simon Lal, John McLaughlin, Josephine Barlow, Massimo D'Amato, Giampaolo Giacovelli, Andrea Varro, Graham J. Dockray, and David G. Thompson

Cholecystokinin pathways modulate sensations induced by gastric distension in humans
Am J Physiol Gastrointest Liver Physiol 287: G72-G79, 2004. First published February 5, 2004; 10.1152/ajpgi.00351.2003 [Abstract] [Full Text] [PDF]  

Yoshikuni Nagashio, Hiroshi Asaumi, Shiro Watanabe, Yoko Nomiyama, Masashi Taguchi, Mitsuo Tashiro, Takeshi Sugaya, and Makoto Otsuki

Angiotensin II type 1 receptor interaction is an important regulator for the development of pancreatic fibrosis in mice
Am J Physiol Gastrointest Liver Physiol 287: G170-G177, 2004. First published March 11, 2004; 10.1152/ajpgi.00005.2004 [Abstract] [Full Text] [PDF]  

Takayuki Mazda, Hiroshi Yamamoto, Masaki Fujimura, and Mineko Fujimiya

Gastric distension-induced release of 5-HT stimulates c-fos expression in specific brain nuclei via 5-HT3 receptors in conscious rats
Am J Physiol Gastrointest Liver Physiol 287: G228-G235, 2004. First published December 18, 2003; 10.1152/ajpgi.00373.2003 [Abstract] [Full Text] [PDF]  

Diana D. H. Thomas, Ning Weng, and Guy E. Groblewski

Secretagogue-induced translocation of CRHSP-28 within an early apical endosomal compartment in acinar cells
Am J Physiol Gastrointest Liver Physiol 287: G253-G263, 2004. First published February 19, 2004; 10.1152/ajpgi.00033.2004 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

Monica Porras, María Teresa Martín, Mercè Soler, and Patri Vergara

Intestinal motor disorders associated with cyclical bacterial overgrowth in a rat model of enteritis
Am J Physiol Gastrointest Liver Physiol 287: G58-G64, 2004. First published February 12, 2004; 10.1152/ajpgi.00513.2003 [Abstract] [Full Text] [PDF]  

Vikas Bhalla, Jianmin Liu, James L. Puckett, and Ravinder K. Mittal

Symptom hypersensitivity to acid infusion is associated with hypersensitivity of esophageal contractility
Am J Physiol Gastrointest Liver Physiol 287: G65-G71, 2004. First published February 19, 2004; 10.1152/ajpgi.00420.2003 [Abstract] [Full Text] [PDF]  

Xiaochun Bian, Xiaoping Zhou, and James J. Galligan

R-type calcium channels in myenteric neurons of guinea pig small intestine
Am J Physiol Gastrointest Liver Physiol 287: G134-G142, 2004. First published February 26, 2004; 10.1152/ajpgi.00532.2003 [Abstract] [Full Text] [PDF]  

E. E. Daniel, Gregory Bodie, Marco Mannarino, Geoffrey Boddy, and Woo-Jung Cho

Changes in membrane cholesterol affect caveolin-1 localization and ICC-pacing in mouse jejunum
Am J Physiol Gastrointest Liver Physiol 287: G202-G210, 2004. First published February 19, 2004; 10.1152/ajpgi.00356.2003 [Abstract] [Full Text] [PDF]  

Xiaochun Jin, Anna P. Malykhina, Florea Lupu, and Hamid I. Akbarali

Altered gene expression and increased bursting activity of colonic smooth muscle ATP-sensitive K⁺ channels in experimental colitis
Am J Physiol Gastrointest Liver Physiol 287: G274-G285, 2004. First published February 12, 2004; 10.1152/ajpgi.00472.2003 [Abstract] [Full Text] [PDF]  

Asensio A. González, Ricard Farré, and Pere Clavé

Different responsiveness of excitatory and inhibitory enteric motor neurons in the human esophagus to electrical field stimulation and to nicotine
Am J Physiol Gastrointest Liver Physiol 287: G299-G306, 2004. First published March 11, 2004; 10.1152/ajpgi.00534.2003 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

M. Arredondo, V. Cambiazo, L. Tapia, M. González-Agüero, M. T. Núñez, R. Uauy, and M. González

Copper overload affects copper and iron metabolism in Hep-G2 cells
Am J Physiol Gastrointest Liver Physiol 287: G27-G32, 2004. First published February 26, 2004; 10.1152/ajpgi.00297.2003 [Abstract] [Full Text] [PDF]  

Kousei Ito, Tomokazu Koresawa, Koichi Nakano, and Toshiharu Horie

Mrp2 is involved in benzylpenicillin-induced choleresis
Am J Physiol Gastrointest Liver Physiol 287: G42-G49, 2004; 10.1152/ajpgi.00416.2003 [Abstract] [Full Text] [PDF]  

Norihisa Ishimura, Steven F. Bronk, and Gregory J. Gores

Inducible nitric oxide synthase upregulates cyclooxygenase-2 in mouse cholangiocytes promoting cell growth
Am J Physiol Gastrointest Liver Physiol 287: G88-G95, 2004. First published February 19, 2004; 10.1152/ajpgi.00539.2003 [Abstract] [Full Text] [PDF]  

Philip Hilgard, Mark J. Czaja, Guido Gerken, and Richard J. Stockert

Proapoptotic function of protein kinase CK2" is mediated by a JNK signaling cascade
Am J Physiol Gastrointest Liver Physiol 287: G192-G201, 2004. First published February 12, 2004; 10.1152/ajpgi.00507.2003 [Abstract] [Full Text] [PDF]  

Jaspreet S. Gujral, Jack A. Hinson, Anwar Farhood, and Hartmut Jaeschke

NADPH oxidase-derived oxidant stress is critical for neutrophil cytotoxicity during endotoxemia
Am J Physiol Gastrointest Liver Physiol 287: G243-G252, 2004. First published March 25, 2004; 10.1152/ajpgi.00287.2003 [Abstract] [Full Text] [PDF]  

Atul Sahai, Padmini Malladi, Hector Melin-Aldana, Richard M. Green, and Peter F. Whitington

Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model
Am J Physiol Gastrointest Liver Physiol 287: G264-G273, 2004. First published March 25, 2004; 10.1152/ajpgi.00002.2004 [Abstract] [Full Text] [PDF]  

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