ESSAYS ON APS CLASSIC PAPERS:

Hershel Raff, Dale Benos, and Margaret Reich

Editorial  Introduction to the classic papers commemorating the APS Legacy Project
Am J Physiol Gastrointest Liver Physiol 287: G939-G940, 2004; doi:10.1152/classicessays.00001.2004 [Full Text] [PDF]  

Marshall H. Montrose

Editorial Focus  The basis for transport across epithelial cells
Am J Physiol Gastrointest Liver Physiol 287: G941-G942, 2004; doi:10.1152/classicessays.00014.2004 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Liyong Wang, Anna Klopot, Jean-Noel Freund, Lauren N. Dowling, Stephen D. Krasinski, and James C. Fleet

Control of differentiation-induced calbindin-D_9k gene expression in Caco-2 cells by cdx-2 and HNF-1
Am J Physiol Gastrointest Liver Physiol 287: G943-G953, 2004. First published June 24, 2004; doi:10.1152/ajpgi.00121.2004 [Abstract] [Full Text] [PDF]  

Jun Wu, Fuli Liu, Åke Nilsson, and Rui-Dong Duan

Pancreatic trypsin cleaves intestinal alkaline sphingomyelinase from mucosa and enhances the sphingomyelinase activity
Am J Physiol Gastrointest Liver Physiol 287: G967-G973, 2004. First published June 17, 2004; doi:10.1152/ajpgi.00190.2004 [Abstract] [Full Text] [PDF]  

Eiji Nakamura, Takashi Kataoka, Kazuharu Furutani, Keisuke Jimbo, Takeshi Aihara, Satoshi Tanaka, Atsushi Ichikawa, Hiroshi Ohtsu, and Susumu Okabe

Lack of histamine alters gastric mucosal morphology: comparison of histidine decarboxylase-deficient and mast cell-deficient mice
Am J Physiol Gastrointest Liver Physiol 287: G1053-G1061, 2004. First published July 22, 2004; doi:10.1152/ajpgi.00353.2003 [Abstract] [Full Text] [PDF]  

Joyce K. Divine, Lora J. Staloch, Hanna Haveri, Christina M. Jacobsen, David B. Wilson, Markku Heikinheimo, and Theodore C. Simon

GATA-4, GATA-5, and GATA-6 activate the rat liver fatty acid binding protein gene in concert with HNF-1
Am J Physiol Gastrointest Liver Physiol 287: G1086-G1099, 2004. First published January 8, 2004; doi:10.1152/ajpgi.00421.2003 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

James L. Watson, Sara Ansari, Heather Cameron, Arthur Wang, Mahmood Akhtar, and Derek M. McKay

Green tea polyphenol (–)-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN- but not by IL-4
Am J Physiol Gastrointest Liver Physiol 287: G954-G961, 2004. First published July 1, 2004; doi:10.1152/ajpgi.00302.2003 [Abstract] [Full Text] [PDF]  

Tanja Sobko, Claudia Reinders, Elisabeth Norin, Tore Midtvedt, Lars E. Gustafsson, and Jon O. Lundberg

Gastrointestinal nitric oxide generation in germ-free and conventional rats
Am J Physiol Gastrointest Liver Physiol 287: G993-G997, 2004. First published July 15, 2004; doi:10.1152/ajpgi.00203.2004 [Abstract] [Full Text] [PDF]  

Jennifer R. O'Hara, Winnie Ho, David R. Linden, Gary M. Mawe, and Keith A. Sharkey

Enteroendocrine cells and 5-HT availability are altered in mucosa of guinea pigs with TNBS ileitis
Am J Physiol Gastrointest Liver Physiol 287: G998-G1007, 2004. First published July 1, 2004; doi:10.1152/ajpgi.00090.2004 [Abstract] [Full Text] [PDF]  

Hiroyuki Ogawa, Mitsutoshi Iimura, Lars Eckmann, and Martin F. Kagnoff

Regulated production of the chemokine CCL28 in human colon epithelium
Am J Physiol Gastrointest Liver Physiol 287: G1062-G1069, 2004. First published July 8, 2004; doi:10.1152/ajpgi.00162.2004 [Abstract] [Full Text] [PDF]  

Lixin Wang, Vasantha Kolachala, Baljit Walia, Srividya Balasubramanian, Randy A. Hall, Didier Merlin, and Shanthi V. Sitaraman

Agonist-induced polarized trafficking and surface expression of the adenosine 2b receptor in intestinal epithelial cells: role of SNARE proteins
Am J Physiol Gastrointest Liver Physiol 287: G1100-G1107, 2004. First published July 15, 2004; doi:10.1152/ajpgi.00164.2004 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

Clinton Ng, Mark Danta, Gillian Prott, Caro-Anne Badcock, John Kellow, and Allison Malcolm

Modulatory influences on antegrade and retrograde tonic reflexes in the colon and rectum
Am J Physiol Gastrointest Liver Physiol 287: G962-G966, 2004. First published July 1, 2004; doi:10.1152/ajpgi.00460.2003 [Abstract] [Full Text] [PDF]  

Giovanni Sarnelli, Daniel Sifrim, Jozef Janssens, and Jan Tack

Influence of sildenafil on gastric sensorimotor function in humans
Am J Physiol Gastrointest Liver Physiol 287: G988-G992, 2004; doi:10.1152/ajpgi.00419.2003 [Abstract] [Full Text] [PDF]  

X.-C. Bian, L. F. Heffer, R. M. Gwynne, J. C. Bornstein, and P. P. Bertrand

Synaptic transmission in simple motility reflex pathways excited by distension in guinea pig distal colon
Am J Physiol Gastrointest Liver Physiol 287: G1017-G1027, 2004. First published July 15, 2004; doi:10.1152/ajpgi.00039.2004 [Abstract] [Full Text] [PDF]  

L. K. Bryant, R. J. Fraser, R. Vozzo, B. Zacharakis, G. M. Matthews, and R. Butler

Stimulation of small intestinal burst activity in the postprandial state differentially affects lipid and glucose absorption in healthy adult humans
Am J Physiol Gastrointest Liver Physiol 287: G1028-G1034, 2004. First published June 10, 2004; doi:10.1152/ajpgi.00091.2004 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Carmen G. Lechuga, Zamira H. Hernández-Nazara, José-Alfredo Domínguez Rosales, Elena R. Morris, Ana Rosa Rincón, Ana María Rivas-Estilla, Andrés Esteban-Gamboa, and Marcos Rojkind

TGF-1 modulates matrix metalloproteinase-13 expression in hepatic stellate cells by complex mechanisms involving p38MAPK, PI3-kinase, AKT, and p70^S6k
Am J Physiol Gastrointest Liver Physiol 287: G974-G987, 2004. First published July 8, 2004; doi:10.1152/ajpgi.00264.2003 [Abstract] [Full Text] [PDF]  

Marieke G. L. Elferink, Peter Olinga, Annelies L. Draaisma, Marjolijn T. Merema, Klaas Nico Faber, Maarten J. H. Slooff, Dirk K. F. Meijer, and Geny M. M. Groothuis

LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process
Am J Physiol Gastrointest Liver Physiol 287: G1008-G1016, 2004. First published June 17, 2004; doi:10.1152/ajpgi.00071.2004 [Abstract] [Full Text] [PDF]  

Atul Sahai, Padmini Malladi, Xiaomin Pan, Rachelle Paul, Hector Melin-Aldana, Richard M. Green, and Peter F. Whitington

Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin
Am J Physiol Gastrointest Liver Physiol 287: G1035-G1043, 2004. First published July 15, 2004; doi:10.1152/ajpgi.00199.2004 [Abstract] [Full Text] [PDF]  

Barbara Jaruga, Feng Hong, Won-Ho Kim, and Bin Gao

IFN-/STAT1 acts as a proinflammatory signal in T cell-mediated hepatitis via induction of multiple chemokines and adhesion molecules: a critical role of IRF-1
Am J Physiol Gastrointest Liver Physiol 287: G1044-G1052, 2004. First published July 8, 2004; doi:10.1152/ajpgi.00184.2004 [Abstract] [Full Text] [PDF]  

Daqing Gao, Chiming Wei, Lei Chen, Jiawen Huang, Shiqi Yang, and Anna Mae Diehl

Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease
Am J Physiol Gastrointest Liver Physiol 287: G1070-G1077, 2004. First published July 1, 2004; doi:10.1152/ajpgi.00228.2004 [Abstract] [Full Text] [PDF]  

Kengo Tomita, Toshifumi Azuma, Naoto Kitamura, Gen Tamiya, Satoshi Ando, Hiroshi Nagata, Shinzo Kato, Sayaka Inokuchi, Takeshi Nishimura, Hiromasa Ishii, and Toshifumi Hibi

Leptin deficiency enhances sensitivity of rats to alcoholic steatohepatitis through suppression of metallothionein
Am J Physiol Gastrointest Liver Physiol 287: G1078-G1085, 2004; doi:10.1152/ajpgi.00107.2004 [Abstract] [Full Text] [PDF]  

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