THEME:

Gert Van Assche and Paul Rutgeerts

Physiological Basis for Novel Drug Therapies Used to Treat the Inflammatory Bowel Diseases I. Immunology and therapeutic potential of antiadhesion molecule therapy in inflammatory bowel disease
Am J Physiol Gastrointest Liver Physiol 288: G169-G174, 2005; doi:10.1152/ajpgi.00423.2004 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Hua Xu, Jennifer K. Uno, Michael Inouye, James F. Collins, and Fayez K. Ghishan

NF1 transcriptional factor(s) is required for basal promoter activation of the human intestinal NaPi-IIb cotransporter gene
Am J Physiol Gastrointest Liver Physiol 288: G175-G181, 2005. First published September 30, 2004; doi:10.1152/ajpgi.00396.2004 [Abstract] [Full Text] [PDF]  

Takashi Joh, Tadayuki Oshima, Nobuo Takahashi, Hiroshi Kaneko, Makoto Sasaki, Hiromi Kataoka, Katsushi Watanabe, Masashi Sobue, Hideo Suzuki, Tomoyuki Nomura, Hirotaka Ohara, and Makoto Itoh

Evaluation of early gastric mucosal permeability induced by central thyrotropin-releasing hormone administration
Am J Physiol Gastrointest Liver Physiol 288: G230-G234, 2005. First published October 21, 2004; doi:10.1152/ajpgi.00100.2004 [Abstract] [Full Text] [PDF]  

Kenji Kusumoto, Tsukasa Kawahara, Yuki Kuwano, Shigetada Teshima-Kondo, Kyoko Morita, Kyoichi Kishi, and Kazuhito Rokutan

Ecabet sodium inhibits Helicobacter pylori lipopolysaccharide-induced activation of NADPH oxidase 1 or apoptosis of guinea pig gastric mucosal cells
Am J Physiol Gastrointest Liver Physiol 288: G300-G307, 2005. First published September 30, 2004; doi:10.1152/ajpgi.00274.2004 [Abstract] [Full Text] [PDF]  

Yoko Shinji, Taku Tsukui, Atsushi Tatsuguchi, Kei Shinoki, Masafumi Kusunoki, Kenji Suzuki, Tetsuro Hiratsuka, Ken Wada, Seiji Futagami, Kazumasa Miyake, Katya Gudis, and Choitsu Sakamoto

Induced microsomal PGE synthase-1 is involved in cyclooxygenase-2-dependent PGE2 production in gastric fibroblasts
Am J Physiol Gastrointest Liver Physiol 288: G308-G315, 2005. First published September 30, 2004; doi:10.1152/ajpgi.00313.2004 [Abstract] [Full Text] [PDF]  

Jennifer M. Smith, Priscilla A. Johanesen, Michael K. Wendt, David G. Binion, and Michael B. Dwinell

CXCL12 activation of CXCR4 regulates mucosal host defense through stimulation of epithelial cell migration and promotion of intestinal barrier integrity
Am J Physiol Gastrointest Liver Physiol 288: G316-G326, 2005. First published September 9, 2004; doi:10.1152/ajpgi.00208.2004 [Abstract] [Full Text] [PDF]  

Laetitia Charrier, Yutao Yan, Adel Driss, Christian L. Laboisse, Shanthi V. Sitaraman, and Didier Merlin

ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers
Am J Physiol Gastrointest Liver Physiol 288: G346-G353, 2005. First published September 9, 2004; doi:10.1152/ajpgi.00262.2004 [Abstract] [Full Text] [PDF]  

Sachiyo Nomura, Hirokazu Yamaguchi, Masako Ogawa, Timothy C. Wang, Jeffrey R. Lee, and James R. Goldenring

Alterations in gastric mucosal lineages induced by acute oxyntic atrophy in wild-type and gastrin-deficient mice
Am J Physiol Gastrointest Liver Physiol 288: G362-G375, 2005; doi:10.1152/ajpgi.00160.2004 [Abstract] [Full Text] [PDF]  

Catherine S. Chew, Curtis T. Okamoto, Xunsheng Chen, and Hai Yan Qin

IQGAPs are differentially expressed and regulated in polarized gastric epithelial cells
Am J Physiol Gastrointest Liver Physiol 288: G376-G387, 2005. First published September 30, 2004; doi:10.1152/ajpgi.00290.2004 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

John D. Linehan, George Kolios, Vassilis Valatas, Duncan A. F. Robertson, and John Westwick

Effect of corticosteroids on nitric oxide production in inflammatory bowel disease: are leukocytes the site of action?
Am J Physiol Gastrointest Liver Physiol 288: G261-G267, 2005. First published September 16, 2004; doi:10.1152/ajpgi.00336.2004 [Abstract] [Full Text] [PDF]  

Hongzhi Xu, Katarzyna Korneszczuk, Amel Karaa, Tian Lin, Mark G. Clemens, and Jian X. Zhang

Thromboxane A₂ from Kupffer cells contributes to the hyperresponsiveness of hepatic portal circulation to endothelin-1 in endotoxemic rats
Am J Physiol Gastrointest Liver Physiol 288: G277-G283, 2005; doi:10.1152/ajpgi.00256.2004 [Abstract] [Full Text] [PDF]  

Anupriya Sharma, Xiaohong Tao, Arun Gopal, Brooke Ligon, Patricia Andrade-Gordon, Michael L. Steer, and George Perides

Protection against acute pancreatitis by activation of protease-activated receptor-2
Am J Physiol Gastrointest Liver Physiol 288: G388-G395, 2005. First published September 30, 2004; doi:10.1152/ajpgi.00341.2004 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Terence Chiu, Chintda Santiskulvong, and Enrique Rozengurt

EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway
Am J Physiol Gastrointest Liver Physiol 288: G182-G194, 2005. First published September 9, 2004; doi:10.1152/ajpgi.00200.2004 [Abstract] [Full Text] [PDF]  

Nan Li, Qingding Wang, Jing Li, Xiaofu Wang, Mark R. Hellmich, Srinivasan Rajaraman, George H. Greeley, Jr., Courtney M. Townsend, Jr., and B. Mark Evers

Inhibition of mitochondrial gene transcription suppresses neurotensin secretion in the human carcinoid cell line BON
Am J Physiol Gastrointest Liver Physiol 288: G213-G220, 2005. First published September 9, 2004; doi:10.1152/ajpgi.00043.2004 [Abstract] [Full Text] [PDF]  

A. Chaudhuri, T. R. Kolodecik, and F. S. Gorelick

Effects of increased intracellular cAMP on carbachol-stimulated zymogen activation, secretion, and injury in the pancreatic acinar cell
Am J Physiol Gastrointest Liver Physiol 288: G235-G243, 2005. First published September 30, 2004; doi:10.1152/ajpgi.00334.2004 [Abstract] [Full Text] [PDF]  

Jean M. Lay, Gina Bane, Cynthia S. Brunkan, Jennifer Davis, Lymari Lopez-Diaz, and Linda C. Samuelson

Enteroendocrine cell expression of a cholecystokinin gene construct in transgenic mice and cultured cells
Am J Physiol Gastrointest Liver Physiol 288: G354-G361, 2005. First published October 14, 2004; doi:10.1152/ajpgi.00356.2004 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

Sita Somara, Haiyan Pang, and Khalil N. Bitar

Agonist-induced association of tropomyosin with protein kinase C in colonic smooth muscle
Am J Physiol Gastrointest Liver Physiol 288: G268-G276, 2005. First published October 14, 2004; doi:10.1152/ajpgi.00330.2004 [Abstract] [Full Text] [PDF]  

Y. M. Kang, K. Lamb, G. F. Gebhart, and K. Bielefeldt

Experimentally induced ulcers and gastric sensory-motor function in rats
Am J Physiol Gastrointest Liver Physiol 288: G284-G291, 2005. First published September 23, 2004; doi:10.1152/ajpgi.00250.2004 [Abstract] [Full Text] [PDF]  

Michelle C. Buresi, Nathalie Vergnolle, Keith A. Sharkey, Catherine M. Keenan, Patricia Andrade-Gordon, Giuseppe Cirino, Donatella Cirillo, Morley D. Hollenberg, and Wallace K. MacNaughton

Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro
Am J Physiol Gastrointest Liver Physiol 288: G337-G345, 2005. First published September 2, 2004; doi:10.1152/ajpgi.00112.2004 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Lisa M. Torres, Jonathan Youngner, and Andrea Romani

Role of glucose in modulating Mg²⁺ homeostasis in liver cells from starved rats
Am J Physiol Gastrointest Liver Physiol 288: G195-G206, 2005; doi:10.1152/ajpgi.00488.2003 [Abstract] [Full Text] [PDF]  

Wenxian Nie, Seth Sweetser, Mary Rinella, and Richard M. Green

Transcriptional regulation of murine Slc22a1 (Oct1) by peroxisome proliferator agonist receptor- and -
Am J Physiol Gastrointest Liver Physiol 288: G207-G212, 2005. First published September 30, 2004; doi:10.1152/ajpgi.00057.2004 [Abstract] [Full Text] [PDF]  

Wen-Zhi Lan, Houria Abbas, Hung D. Lam, Anne-Marie Lemay, and Ceredwyn E. Hill

Contribution of a time-dependent and hyperpolarization-activated chloride conductance to currents of resting and hypotonically shocked rat hepatocytes
Am J Physiol Gastrointest Liver Physiol 288: G221-G229, 2005. First published September 9, 2004; doi:10.1152/ajpgi.00226.2004 [Abstract] [Full Text] [PDF]  

Tomoharu Shimizu, Laszlo Szalay, Mashkoor A. Choudhry, Martin G. Schwacha, Loring W. Rue, III, Kirby I. Bland, and Irshad H. Chaudry

Mechanism of salutary effects of androstenediol on hepatic function after trauma-hemorrhage: role of endothelial and inducible nitric oxide synthase
Am J Physiol Gastrointest Liver Physiol 288: G244-G250, 2005. First published September 23, 2004; doi:10.1152/ajpgi.00387.2004 [Abstract] [Full Text] [PDF]  

N. Balasubramaniyan, Mohammad Shahid, Frederick J. Suchy, and M. Ananthanarayanan

Multiple mechanisms of ontogenic regulation of nuclear receptors during rat liver development
Am J Physiol Gastrointest Liver Physiol 288: G251-G260, 2005. First published September 23, 2004; doi:10.1152/ajpgi.00351.2004 [Abstract] [Full Text] [PDF]  

Ronald J. Jandacek, Nicole Anderson, Min Liu, Shuqin Zheng, Qing Yang, and Patrick Tso

Effects of yo-yo diet, caloric restriction, and olestra on tissue distribution of hexachlorobenzene
Am J Physiol Gastrointest Liver Physiol 288: G292-G299, 2005. First published October 28, 2004; doi:10.1152/ajpgi.00285.2004 [Abstract] [Full Text] [PDF]  

Aldo D. Mottino, Fernando A. Crocenzi, Enrique J. Sánchez Pozzi, Luis M. Veggi, Marcelo G. Roma, and Mary Vore

Role of microtubules in estradiol-17-D-glucuronide-induced alteration of canalicular Mrp2 localization and activity
Am J Physiol Gastrointest Liver Physiol 288: G327-G336, 2005. First published September 16, 2004; doi:10.1152/ajpgi.00227.2004 [Abstract] [Full Text] [PDF]  

E. S. Baskin-Bey, A. Canbay, S. F. Bronk, N. Werneburg, M. E. Guicciardi, S. L. Nyberg, and G. J. Gores

Cathepsin B inactivation attenuates hepatocyte apoptosis and liver damage in steatotic livers after cold ischemia-warm reperfusion injury
Am J Physiol Gastrointest Liver Physiol 288: G396-G402, 2005. First published October 7, 2004; doi:10.1152/ajpgi.00316.2004 [Abstract] [Full Text] [PDF]  

REPORTS:

Shanthi V. Sitaraman, Jan-Michael Klapproth, Daniel A. Moore, III, Carol Landers, Stephan Targan, Ifor R. Williams, and Andrew T. Gewirtz

Elevated flagellin-specific immunoglobulins in Crohn's disease
Am J Physiol Gastrointest Liver Physiol 288: G403-G406, 2005. First published September 23, 2004; doi:10.1152/ajpgi.00357.2004 [Abstract] [Full Text] [PDF]  

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