THEMES:

Geraldine Canny and Sean P. Colgan

Events at the Host-Microbial Interface of the Gastrointestinal Tract I. Adaptation to a microbial world: role of epithelial bactericidal/permeability-increasing protein
Am J Physiol Gastrointest Liver Physiol 288: G593-G597, 2005; doi:10.1152/ajpgi.00506.2004 [Abstract] [Full Text] [PDF]  

Hamid I. Akbarali

Signal-Transduction Pathways that Regulate Smooth Muscle Function II. Receptor-ion channel coupling mechanisms in gastrointestinal smooth muscle
Am J Physiol Gastrointest Liver Physiol 288: G598-G602, 2005; doi:10.1152/ajpgi.00402.2004 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Sabine Leonhard-Marek, Friederike Stumpff, Inge Brinkmann, Gerhard Breves, and Holger Martens

Basolateral Mg²⁺/Na⁺ exchange regulates apical nonselective cation channel in sheep rumen epithelium via cytosolic Mg²⁺
Am J Physiol Gastrointest Liver Physiol 288: G630-G645, 2005. First published November 18, 2004; doi:10.1152/ajpgi.00275.2004 [Abstract] [Full Text] [PDF]  

Zachary M. Sellers, Debbie Childs, Jimmy Y. C. Chow, Anders J. Smith, Daniel L. Hogan, Jon I. Isenberg, Hui Dong, Kim E. Barrett, and Vijaya S. Pratha

Heat-stable enterotoxin of Escherichia coli stimulates a non-CFTR-mediated duodenal bicarbonate secretory pathway
Am J Physiol Gastrointest Liver Physiol 288: G654-G663, 2005. First published October 28, 2004; doi:10.1152/ajpgi.00386.2004 [Abstract] [Full Text] [PDF]  

Yuriko Shimizu, Satohiro Masuda, Kumiko Nishihara, Lin Ji, Masahiro Okuda, and Ken-ichi Inui

Increased protein level of PEPT1 intestinal H⁺-peptide cotransporter upregulates absorption of glycylsarcosine and ceftibuten in 5/6 nephrectomized rats
Am J Physiol Gastrointest Liver Physiol 288: G664-G670, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00270.2004 [Abstract] [Full Text] [PDF]  

Donna L. Arvans, Stephan R. Vavricka, Hongyu Ren, Mark W. Musch, Lisa Kang, Flavio G. Rocha, Alvaro Lucioni, Jerrold R. Turner, John Alverdy, and Eugene B. Chang

Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72
Am J Physiol Gastrointest Liver Physiol 288: G696-G704, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00206.2004 [Abstract] [Full Text] [PDF]  

Solange Abdulnour-Nakhoul, Nazih L. Nakhoul, Scott A. Wheeler, Paul Wang, Eric R. Swenson, and Roy C. Orlando

HCO₃^– secretion in the esophageal submucosal glands
Am J Physiol Gastrointest Liver Physiol 288: G736-G744, 2005. First published December 2, 2004; doi:10.1152/ajpgi.00055.2004 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

Hirotada Akiho, Paola Lovato, Yikang Deng, Peter J. M. Ceponis, Patricia Blennerhassett, and Stephen M. Collins

Interleukin-4- and -13-induced hypercontractility of human intestinal muscle cells-implication for motility changes in Crohn's disease
Am J Physiol Gastrointest Liver Physiol 288: G609-G615, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00273.2004 [Abstract] [Full Text] [PDF]  

Paola Brun, Cristina Mastrotto, Elisa Beggiao, Annalisa Stefani, Luisa Barzon, Giacomo C. Sturniolo, Giorgio Palù, and Ignazio Castagliuolo

Neuropeptide neurotensin stimulates intestinal wound healing following chronic intestinal inflammation
Am J Physiol Gastrointest Liver Physiol 288: G621-G629, 2005; doi:10.1152/ajpgi.00140.2004 [Abstract] [Full Text] [PDF]  

Xing-He Weng, Klaus W. Beyenbach, and Andrea Quaroni

Cultured monolayers of the dog jejunum with the structural and functional properties resembling the normal epithelium
Am J Physiol Gastrointest Liver Physiol 288: G705-G717, 2005. First published November 18, 2004; doi:10.1152/ajpgi.00518.2003 [Abstract] [Full Text] [PDF]  

Koushi Oh, Yuji Iimuro, Masaharu Takeuchi, Yasufumi Kaneda, Tsuyoshi Iwasaki, Nobuyuki Terada, Takayuki Matsumoto, Kenji Nakanishi, and Jiro Fujimoto

Ameliorating effect of hepatocyte growth factor on inflammatory bowel disease in a murine model
Am J Physiol Gastrointest Liver Physiol 288: G729-G735, 2005. First published November 18, 2004; doi:10.1152/ajpgi.00438.2004 [Abstract] [Full Text] [PDF]  

Eriko Okada, Motomi Yamazaki, Masanobu Tanabe, Tsutomu Takeuchi, Masanobu Nanno, Shigeru Oshima, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Takanori Kanai, Toshifumi Hibi, and Mamoru Watanabe

IL-7 exacerbates chronic colitis with expansion of memory IL-7R^high CD4⁺ mucosal T cells in mice
Am J Physiol Gastrointest Liver Physiol 288: G745-G754, 2005. First published November 18, 2004; doi:10.1152/ajpgi.00276.2004 [Abstract] [Full Text] [PDF]  

Jessica A. Clark, Robert H. Lane, Nicole K. MacLennan, Hana Holubec, Katerina Dvorakova, Melissa D. Halpern, Catherine S. Williams, Claire M. Payne, and Bohuslav Dvorak

Epidermal growth factor reduces intestinal apoptosis in an experimental model of necrotizing enterocolitis
Am J Physiol Gastrointest Liver Physiol 288: G755-G762, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00172.2004 [Abstract] [Full Text] [PDF]  

Pawel R. Kiela, Anna J. Midura, Nesrin Kuscuoglu, Shivanand D. Jolad, Anikó M. Sólyom, David G. Besselsen, Barbara N. Timmermann, and Fayez K. Ghishan

Effects of Boswellia serrata in mouse models of chemically induced colitis
Am J Physiol Gastrointest Liver Physiol 288: G798-G808, 2005. First published November 11, 2004; doi:10.1152/ajpgi.00433.2004 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Xuesong Chen, Hai-Ying Zhang, Kristin Pavlish, and Joseph N. Benoit

Effects of chronic portal hypertension on small heat-shock proteins in mesenteric arteries
Am J Physiol Gastrointest Liver Physiol 288: G616-G620, 2005. First published October 28, 2004; doi:10.1152/ajpgi.00439.2004 [Abstract] [Full Text] [PDF]  

Damien Matusiak, Sarah Glover, Rajkumar Nathaniel, Kristina Matkowskyj, Jianxin Yang, and Richard V. Benya

Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon
Am J Physiol Gastrointest Liver Physiol 288: G718-G728, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00156.2004 [Abstract] [Full Text] [PDF]  

Ji Eun Lee, Joo Hyun Nam, and Sung Joon Kim

Muscarinic activation of Na⁺-dependent ion transporters and modulation by bicarbonate in rat submandibular gland acinus
Am J Physiol Gastrointest Liver Physiol 288: G822-G831, 2005. First published November 11, 2004; doi:10.1152/ajpgi.00406.2004 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

John E. Pandolfino, Guoxiang Shi, Qing Zhang, and Peter J. Kahrilas

Absence of a deglutitive inhibition equivalent with secondary peristalsis
Am J Physiol Gastrointest Liver Physiol 288: G671-G676, 2005. First published December 16, 2004; doi:10.1152/ajpgi.00388.2004 [Abstract] [Full Text] [PDF]  

Ling Cheng, Weibiao Cao, Jose Behar, Piero Biancani, and Karen M. Harnett

Inflammation induced changes in arachidonic acid metabolism in cat LES circular muscle
Am J Physiol Gastrointest Liver Physiol 288: G787-G797, 2005. First published November 18, 2004; doi:10.1152/ajpgi.00327.2004 [Abstract] [Full Text] [PDF]  

Yaohui Zhu, Andrea Mucci, and Jan D. Huizinga

Inwardly rectifying chloride channel activity in intestinal pacemaker cells
Am J Physiol Gastrointest Liver Physiol 288: G809-G821, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00301.2004 [Abstract] [Full Text] [PDF]  

Yukari Takeda, Sean M. Ward, Kenton M. Sanders, and Sang Don Koh

Effects of the gap junction blocker glycyrrhetinic acid on gastrointestinal smooth muscle cells
Am J Physiol Gastrointest Liver Physiol 288: G832-G841, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00389.2004 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Hai-Ying Zhang, Yuichi Shirasawa, Xuesong Chen, Hong Yu, and Joseph N. Benoit

Impaired agonist-dependent myosin phosphorylation and decreased RhoA in rat portal hypertensive mesenteric vasculature
Am J Physiol Gastrointest Liver Physiol 288: G603-G608, 2005. First published October 28, 2004; doi:10.1152/ajpgi.00116.2004 [Abstract] [Full Text] [PDF]  

Marcel J. C. Bijvelds, Inez Bronsveld, Rick Havinga, Maarten Sinaasappel, Hugo R. de Jonge, and Henkjan J. Verkade

Fat absorption in cystic fibrosis mice is impeded by defective lipolysis and post-lipolytic events
Am J Physiol Gastrointest Liver Physiol 288: G646-G653, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00295.2004 [Abstract] [Full Text] [PDF]  

Jens H. Henriksen, Søren Møller, Stefan Fuglsang, and Flemming Bendtsen

Detection of early central circulatory transits in patients with cirrhosis by gamma variate fit of indicator dilution profiles
Am J Physiol Gastrointest Liver Physiol 288: G677-G684, 2005. First published December 2, 2004; doi:10.1152/ajpgi.00201.2004 [Abstract] [Full Text] [PDF]  

Asmeen Jahan and John Y. L. Chiang

Cytokine regulation of human sterol 12-hydroxylase (CYP8B1) gene
Am J Physiol Gastrointest Liver Physiol 288: G685-G695, 2005. First published November 18, 2004; doi:10.1152/ajpgi.00207.2004 [Abstract] [Full Text] [PDF]  

Mariona Graupera, Sandra March, Pablo Engel, Juan Rodés, Jaume Bosch, and Joan-Carles García-Pagán

Sinusoidal endothelial COX-1-derived prostanoids modulate the hepatic vascular tone of cirrhotic rat livers
Am J Physiol Gastrointest Liver Physiol 288: G763-G770, 2005. First published November 18, 2004; doi:10.1152/ajpgi.00300.2004 [Abstract] [Full Text] [PDF]  

Pascal Frei, Bo Gao, Bruno Hagenbuch, Alfonso Mate, Jürg Biber, Heini Murer, Peter J. Meier, and Bruno Stieger

Identification and localization of sodium-phosphate cotransporters in hepatocytes and cholangiocytes of rat liver
Am J Physiol Gastrointest Liver Physiol 288: G771-G778, 2005. First published November 24, 2004; doi:10.1152/ajpgi.00272.2004 [Abstract] [Full Text] [PDF]  

R. Brian Doctor, Thomas Matzakos, Ryan McWilliams, Sylene Johnson, Andrew P. Feranchak, and J. Gregory Fitz

Purinergic regulation of cholangiocyte secretion: identification of a novel role for P2X receptors
Am J Physiol Gastrointest Liver Physiol 288: G779-G786, 2005. First published November 4, 2004; doi:10.1152/ajpgi.00325.2004 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Junji Ueda, Hiroshi Saito, Hiroaki Watanabe, and B. Mark Evers

Novel and quantitative DNA dot-blotting method for assessment of in vivo proliferation
Am J Physiol Gastrointest Liver Physiol 288: G842-G847, 2005. First published November 11, 2004; doi:10.1152/ajpgi.00463.2004 [Abstract] [Full Text] [PDF]  

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