THEMES:

Jinah Choi and J.-H. James Ou

Mechanisms of Liver Injury. III. Oxidative stress in the pathogenesis of hepatitis C virus
Am J Physiol Gastrointest Liver Physiol 290: G847-G851, 2006; doi:10.1152/ajpgi.00522.2005 [Abstract] [Full Text] [PDF]  

Janardan K. Reddy and M. Sambasiva Rao

Lipid Metabolism and Liver Inflammation. II. Fatty liver disease and fatty acid oxidation
Am J Physiol Gastrointest Liver Physiol 290: G852-G858, 2006; doi:10.1152/ajpgi.00521.2005 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Jason K. Sicklick, Yin-Xiong Li, Alaa Melhem, Eva Schmelzer, Marzena Zdanowicz, Jiawen Huang, Montserrat Caballero, Jeff H. Fair, John W. Ludlow, Randall E. McClelland, Lola M. Reid, and Anna Mae Diehl

Hedgehog signaling maintains resident hepatic progenitors throughout life
Am J Physiol Gastrointest Liver Physiol 290: G859-G870, 2006. First published December 1, 2005; doi:10.1152/ajpgi.00456.2005 [Abstract] [Full Text] [PDF]  

Linda A. Feagins, Nathan Susnow, Hui Ying Zhang, Stephanie Pearson, Charles Owen, William F. Schmalstieg, Lance S. Terada, Stuart J. Spechler, Ruben D. Ramirez, and Rhonda F. Souza

Gain of allelic gene expression for IGF-II occurs frequently in Barrett's esophagus
Am J Physiol Gastrointest Liver Physiol 290: G871-G875, 2006. First published December 8, 2005; doi:10.1152/ajpgi.00383.2005 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Wolfgang Stehr, Nicole P. Bernal, Christopher R. Erwin, Kathryn Q. Bernabe, Jun Guo, and Brad W. Warner

Roles for p21^waf1/cip1 and p27^kip1 during the adaptation response to massive intestinal resection
Am J Physiol Gastrointest Liver Physiol 290: G933-G941, 2006. First published December 1, 2005; doi:10.1152/ajpgi.00235.2005 [Abstract] [Full Text] [PDF]  

Lymari Lopez-Diaz, Karen L. Hinkle, Renu N. Jain, Yana Zavros, Cynthia S. Brunkan, Theresa Keeley, Kathryn A. Eaton, Juanita L. Merchant, Catherine S. Chew, and Linda C. Samuelson

Parietal cell hyperstimulation and autoimmune gastritis in cholera toxin transgenic mice
Am J Physiol Gastrointest Liver Physiol 290: G970-G979, 2006. First published January 6, 2006; doi:10.1152/ajpgi.00461.2005 [Abstract] [Full Text] [PDF]  

Tsutomu Nishida, Shingo Tsuji, Arata Kimura, Masahiko Tsujii, Syuji Ishii, Toshiyuki Yoshio, Shinichiro Shinzaki, Satoshi Egawa, Takanobu Irie, Masakazu Yasumaru, Hideki Iijima, Hiroaki Murata, Sunao Kawano, and Norio Hayashi

Endothelin-1, an ulcer inducer, promotes gastric ulcer healing via mobilizing gastric myofibroblasts and stimulates production of stroma-derived factors
Am J Physiol Gastrointest Liver Physiol 290: G1041-G1050, 2006. First published December 29, 2005; doi:10.1152/ajpgi.00462.2005 [Abstract] [Full Text] [PDF]  

T. Kanai, K. Tanimoto, Y. Nemoto, R. Fujii, S. Makita, T. Totsuka, and M. Watanabe

Naturally arising CD4⁺CD25⁺ regulatory T cells suppress the expansion of colitogenic CD4⁺CD44^highCD62L^– effector memory T cells
Am J Physiol Gastrointest Liver Physiol 290: G1051-G1058, 2006. First published December 22, 2005; doi:10.1152/ajpgi.00429.2005 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

Stephen J. Wigmore, Kenneth C. H. Fearon, James A. Ross, Stephen J. McNally, William J. Welch, and O. James Garden

Febrile-range temperature but not heat shock augments the acute phase response to interleukin-6 in human hepatoma cells
Am J Physiol Gastrointest Liver Physiol 290: G903-G911, 2006. First published December 8, 2005; doi:10.1152/ajpgi.00089.2005 [Abstract] [Full Text] [PDF]  

Elizabeth C. Wick, Steven G. Hoge, Sarah W. Grahn, Edward Kim, Lorna A. Divino, Eileen F. Grady, Nigel W. Bunnett, and Kimberly S. Kirkwood

Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis
Am J Physiol Gastrointest Liver Physiol 290: G959-G969, 2006. First published January 6, 2006; doi:10.1152/ajpgi.00154.2005 [Abstract] [Full Text] [PDF]  

Robert B. Dorman, Christian Wunder, Hamida Saba, Jennifer L. Shoemaker, Lee Ann MacMillan-Crow, and Robert W. Brock

NAD(P)H oxidase contributes to the progression of remote hepatic parenchymal injury and endothelial dysfunction, but not microvascular perfusion deficits
Am J Physiol Gastrointest Liver Physiol 290: G1025-G1032, 2006. First published December 8, 2005; doi:10.1152/ajpgi.00246.2005 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Shizhong Zheng and Anping Chen

Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor
Am J Physiol Gastrointest Liver Physiol 290: G883-G893, 2006. First published November 23, 2005; doi:10.1152/ajpgi.00450.2005 [Abstract] [Full Text] [PDF]  

Edwin C. Thrower, Alexander P. E. Diaz de Villalvilla, Thomas R. Kolodecik, and Fred S. Gorelick

Zymogen activation in a reconstituted pancreatic acinar cell system
Am J Physiol Gastrointest Liver Physiol 290: G894-G902, 2006. First published December 8, 2005; doi:10.1152/ajpgi.00373.2005 [Abstract] [Full Text] [PDF]  

Zuo-Liang Xiao, Weibiao Cao, Piero Biancani, and Jose Behar

Nongenomic effects of progesterone on the contraction of muscle cells from the guinea pig colon
Am J Physiol Gastrointest Liver Physiol 290: 1008-1015, 2006. First published January 6, 2006; doi:10.1152/ajpgi.00382.2005 [Abstract] [Full Text] [PDF]  

Tjalling Bosse, Herbert M. van Wering, Marieke Gielen, Lauren N. Dowling, John J. Fialkovich, Christina M. Piaseckyj, Frank J. Gonzalez, Taro E. Akiyama, Robert K. Montgomery, Richard J. Grand, and Stephen D. Krasinski

Hepatocyte nuclear factor-1 is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo
Am J Physiol Gastrointest Liver Physiol 290: G1016-G1024, 2006. First published October 13, 2005; doi:10.1152/ajpgi.00359.2005 [Abstract] [Full Text] [PDF] [Supplemental Table]  

NEUROREGULATION AND MOTILITY:

H. Gregersen, T. Hausken, J. Yang, S. Ødegaard, and O. H. Gilja

Mechanosensory properties in the human gastric antrum evaluated using B-mode ultrasonography during volume-controlled antral distension
Am J Physiol Gastrointest Liver Physiol 290: G876-G882, 2006. First published November 17, 2005; doi:10.1152/ajpgi.00131.2005 [Abstract] [Full Text] [PDF]  

Michael Camilleri, Adil E. Bharucha, Ryuji Ueno, Duane Burton, George M. Thomforde, Kari Baxter, Sanna McKinzie, and Alan R. Zinsmeister

Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteers
Am J Physiol Gastrointest Liver Physiol 290: G942-G947, 2006; doi:10.1152/ajpgi.00264.2005 [Abstract] [Full Text] [PDF]  

Shirin Kordasti, Maria Sapnara, Evan A. Thomas, Erik Lindstrom, Mikael Forsman, Joel C. Bornstein, and Henrik Sjövall

Effects of cholera toxin on the potential difference and motor responses induced by distension in the rat proximal small intestine in vivo
Am J Physiol Gastrointest Liver Physiol 290: G948-G958, 2006. First published December 15, 2005; doi:10.1152/ajpgi.00267.2005 [Abstract] [Full Text] [PDF]  

Sudip K. Ghosh, John E. Pandolfino, Qing Zhang, Andrew Jarosz, Nimeesh Shah, and Peter J. Kahrilas

Quantifying esophageal peristalsis with high-resolution manometry: a study of 75 asymptomatic volunteers
Am J Physiol Gastrointest Liver Physiol 290: G988-G997, 2006. First published January 12, 2006; doi:10.1152/ajpgi.00510.2005 [Abstract] [Full Text] [PDF]  

John E. Pandolfino, Sudip K. Ghosh, Qing Zhang, Andrew Jarosz, Nimeesh Shah, and Peter J. Kahrilas

Quantifying EGJ morphology and relaxation with high-resolution manometry: a study of 75 asymptomatic volunteers
Am J Physiol Gastrointest Liver Physiol 290: G1033-G1040, 2006. First published February 2, 2006; doi:10.1152/ajpgi.00444.2005 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Tamara Frankenberg, Anuradha Rao, Frank Chen, Jamie Haywood, Benjamin L. Shneider, and Paul A. Dawson

Regulation of the mouse organic solute transporter -, Ost-Ost, by bile acids
Am J Physiol Gastrointest Liver Physiol 290: G912-G922, 2006. First published December 15, 2005; doi:10.1152/ajpgi.00479.2005 [Abstract] [Full Text] [PDF] [Supplemental Materials]  

Gernot Zollner, Martin Wagner, Tarek Moustafa, Peter Fickert, Dagmar Silbert, Judith Gumhold, Andrea Fuchsbichler, Emina Halilbasic, Helmut Denk, Hanns-Ulrich Marschall, and Michael Trauner

Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-/ in the adaptive response to bile acids
Am J Physiol Gastrointest Liver Physiol 290: G923-G932, 2006. First published December 15, 2005; doi:10.1152/ajpgi.00490.2005 [Abstract] [Full Text] [PDF]  

Juan G. Abraldes, Yasuko Iwakiri, Mauricio Loureiro-Silva, Omar Haq, William C. Sessa, and Roberto J. Groszmann

Mild increases in portal pressure upregulate vascular endothelial growth factor and endothelial nitric oxide synthase in the intestinal microcirculatory bed, leading to a hyperdynamic state
Am J Physiol Gastrointest Liver Physiol 290: G980-G987, 2006; doi:10.1152/ajpgi.00336.2005 [Abstract] [Full Text] [PDF]  

Varsha Thakur, Michele T. Pritchard, Megan R. McMullen, and Laura E. Nagy

Adiponectin normalizes LPS-stimulated TNF- production by rat Kupffer cells after chronic ethanol feeding
Am J Physiol Gastrointest Liver Physiol 290: G998-G1007, 2006. First published January 12, 2006; doi:10.1152/ajpgi.00553.2005 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Jiri Petrak, Denisa Myslivcova, Petr Man, Radek Cmejla, Jana Cmejlova, and Daniel Vyoral

Proteomic analysis of iron overload in human hepatoma cells
Am J Physiol Gastrointest Liver Physiol 290: G1059-G1066, 2006. First published January 12, 2006; doi:10.1152/ajpgi.00469.2005 [Abstract] [Full Text] [PDF]  

Anders Bondo Dydensborg, Elizabeth Herring, Joëlle Auclair, Eric Tremblay, and Jean-Francois Beaulieu

Normalizing genes for quantitative RT-PCR in differentiating human intestinal epithelial cells and adenocarcinomas of the colon
Am J Physiol Gastrointest Liver Physiol 290: G1067-G1074, 2006. First published January 6, 2006; doi:10.1152/ajpgi.00234.2005 [Abstract] [Full Text] [PDF]  

REPORTS:

Fabio Quondamatteo, Wolfgang Krick, Yohannes Hagos, Marie-Helen Krüger, Katrin Neubauer-Saile, Rainer Herken, Giuliano Ramadori, Gerhard Burckhardt, and Birgitta C. Burckhardt

Localization of the sulfate/anion exchanger in the rat liver
Am J Physiol Gastrointest Liver Physiol 290: G1075-G1081, 2006. First published December 15, 2005; doi:10.1152/ajpgi.00492.2005 [Abstract] [Full Text] [PDF]  

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