THEMES:

Duan Chen, Takeshi Aihara, Chun-Mei Zhao, Rolf Håkanson, and Susumu Okabe

Differentiation of the Gastric Mucosa I. Role of histamine in control of function and integrity of oxyntic mucosa: understanding gastric physiology through disruption of targeted genes
Am J Physiol Gastrointest Liver Physiol 291: G539-G544, 2006; doi:10.1152/ajpgi.00178.2006 [Abstract] [Full Text] [PDF]  

INVITED REVIEWS:

Sushil K. Sarna

Molecular, functional, and pharmacological targets for the development of gut promotility drugs
Am J Physiol Gastrointest Liver Physiol 291: G545-G555, 2006. First published March 24, 2006; doi:10.1152/ajpgi.00122.2006 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Diana Gallego, Pilar Hernández, Pere Clavé, and Marcel Jiménez

P2Y₁ receptors mediate inhibitory purinergic neuromuscular transmission in the human colon
Am J Physiol Gastrointest Liver Physiol 291: G584-G594, 2006. First published June 1, 2006; doi:10.1152/ajpgi.00474.2005 [Abstract] [Full Text] [PDF]  

O. Bachmann, D. Reichelt, B. Tuo, M. P. Manns, and U. Seidler

Carbachol increases Na⁺-HCO₃^– cotransport activity in murine colonic crypts in a M₃^–, Ca²⁺/calmodulin-, and PKC-dependent manner
Am J Physiol Gastrointest Liver Physiol 291: G650-G657, 2006. First published May 4, 2006; doi:10.1152/ajpgi.00376.2005 [Abstract] [Full Text] [PDF]  

Satish Mistry, John C. Rothwell, David G. Thompson, and Shaheen Hamdy

Modulation of human cortical swallowing motor pathways after pleasant and aversive taste stimuli
Am J Physiol Gastrointest Liver Physiol 291: G666-G671, 2006. First published May 25, 2006; doi:10.1152/ajpgi.00573.2005 [Abstract] [Full Text] [PDF]  

Yanfang Guan, Jin Dong, Lixuan Tackett, Jamie W. Meyer, Gary E. Shull, and Marshall H. Montrose

NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na⁺-dependent acid extrusion mechanism is upregulated in NHE2-null mice
Am J Physiol Gastrointest Liver Physiol 291: G689-G699, 2006. First published May 11, 2006; doi:10.1152/ajpgi.00342.2005 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

Kathleen G. Raman, Penny L. Sappington, Runkuan Yang, Ryan M. Levy, Jose M. Prince, Shiguang Liu, Simon K. Watkins, Ann Marie Schmidt, Timothy R. Billiar, and Mitchell P. Fink

The role of RAGE in the pathogenesis of intestinal barrier dysfunction after hemorrhagic shock
Am J Physiol Gastrointest Liver Physiol 291: G556-G565, 2006. First published June 1, 2006; doi:10.1152/ajpgi.00055.2006 [Abstract] [Full Text] [PDF]  

Theresa F. Wu, Colin J. Carati, Wallace K. MacNaughton, and Pierre-Yves von der Weid

Contractile activity of lymphatic vessels is altered in the TNBS model of guinea pig ileitis
Am J Physiol Gastrointest Liver Physiol 291: G566-G574, 2006. First published May 4, 2006; doi:10.1152/ajpgi.00058.2006 [Abstract] [Full Text] [PDF]  

Caihong Wang, Keely G. McDonald, Jacquelyn S. McDonough, and Rodney D. Newberry

Murine isolated lymphoid follicles contain follicular B lymphocytes with a mucosal phenotype
Am J Physiol Gastrointest Liver Physiol 291: G595-G604, 2006. First published June 15, 2006; doi:10.1152/ajpgi.00525.2005 [Abstract] [Full Text] [PDF]  

Dariusz Stepniak, Liesbeth Spaenij-Dekking, Cristina Mitea, Martine Moester, Arnoud de Ru, Renee Baak-Pablo, Peter van Veelen, Luppo Edens, and Frits Koning

Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease
Am J Physiol Gastrointest Liver Physiol 291: G621-G629, 2006. First published May 11, 2006; doi:10.1152/ajpgi.00034.2006 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

Mitsuyoshi Yamamoto, Munenori Otani, and Makoto Otsuki

A new model of chronic pancreatitis in rats
Am J Physiol Gastrointest Liver Physiol 291: G700-G708, 2006; doi:10.1152/ajpgi.00502.2005 [Abstract] [Full Text] [PDF]  

Takafumi Yuki, Shunji Ishihara, M. A. K. Rumi, Cesar F. Ortega-Cava, Yasunori Kadowaki, Hideaki Kazumori, Norihisa Ishimura, Yuji Amano, Nobuyuki Moriyama, and Yoshikazu Kinoshita

Increased expression of midkine in the rat colon during healing of experimental colitis
Am J Physiol Gastrointest Liver Physiol 291: G735-G743, 2006; doi:10.1152/ajpgi.00388.2005 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Lixin Wang, Nicole R. Basa, Almaas Shaikh, Andrew Luckey, David Heber, David H. St-Pierre, and Yvette Taché

LPS inhibits fasted plasma ghrelin levels in rats: role of IL-1 and PGs and functional implications
Am J Physiol Gastrointest Liver Physiol 291: G611-G620, 2006; doi:10.1152/ajpgi.00533.2005 [Abstract] [Full Text] [PDF]  

Leila Gobejishvili, Shirish Barve, Swati Joshi-Barve, Silvia Uriarte, Zhenyuan Song, and Craig McClain

Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-B activity and TNF expression: relevance to alcoholic liver disease
Am J Physiol Gastrointest Liver Physiol 291: G681-G688, 2006. First published June 1, 2006; doi:10.1152/ajpgi.00098.2006 [Abstract] [Full Text] [PDF]  

Huiping Zhou, Jiean Huang, and Karnam S. Murthy

Molecular cloning and functional expression of a VIP-specific receptor
Am J Physiol Gastrointest Liver Physiol 291: G728-G734, 2006; doi:10.1152/ajpgi.00138.2006 [Abstract] [Full Text] [PDF]  

Min Young Lee, Soo Hyun Park, Yun Jung Lee, Jung Sun Heo, Jang Hern Lee, and Ho Jae Han

EGF-induced inhibition of glucose transport is mediated by PKC and MAPK signal pathways in primary cultured chicken hepatocytes
Am J Physiol Gastrointest Liver Physiol 291: G744-G750, 2006. First published June 15, 2006; doi:10.1152/ajpgi.00551.2005 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

Sita Somara and Khalil N. Bitar

Phosphorylated HSP27 modulates the association of phosphorylated caldesmon with tropomyosin in colonic smooth muscle
Am J Physiol Gastrointest Liver Physiol 291: G630-G639, 2006. First published April 20, 2006; doi:10.1152/ajpgi.00350.2005 [Abstract] [Full Text] [PDF]  

Klaus Bielefeldt, Kenneth Lamb, and G. F. Gebhart

Convergence of sensory pathways in the development of somatic and visceral hypersensitivity
Am J Physiol Gastrointest Liver Physiol 291: G658-G665, 2006. First published February 23, 2006; doi:10.1152/ajpgi.00585.2005 [Abstract] [Full Text] [PDF]  

Weibiao Cao, Ling Cheng, Jose Behar, Piero Biancani, and Karen M. Harnett

IL-1 signaling in cat lower esophageal sphincter circular muscle
Am J Physiol Gastrointest Liver Physiol 291: G672-G680, 2006. First published April 27, 2006; doi:10.1152/ajpgi.00110.2006 [Abstract] [Full Text] [PDF]  

Akira Anan, Edwina S. Baskin-Bey, Hajime Isomoto, Justin L. Mott, Steven F. Bronk, Jeffrey H. Albrecht, and Gregory J. Gores

Proteasome inhibition attenuates hepatic injury in the bile duct-ligated mouse
Am J Physiol Gastrointest Liver Physiol 291: G709-G716, 2006. First published June 22, 2006; doi:10.1152/ajpgi.00126.2006 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Jason K. Sicklick, Steve S. Choi, Marcia Bustamante, Shannon J. McCall, Elizabeth Hernández Pérez, Jiawen Huang, Yin-Xiong Li, Marcos Rojkind, and Anna Mae Diehl

Evidence for epithelial-mesenchymal transitions in adult liver cells
Am J Physiol Gastrointest Liver Physiol 291: G575-G583, 2006. First published May 18, 2006; doi:10.1152/ajpgi.00102.2006 [Abstract] [Full Text] [PDF]  

Wenhui Hu, Sunila Mahavadi, Jiean Huang, Fang Li, and Karnam S. Murthy

Characterization of S1P₁ and S1P₂ receptor function in smooth muscle by receptor silencing and receptor protection
Am J Physiol Gastrointest Liver Physiol 291: G605-G610, 2006. First published May 4, 2006; doi:10.1152/ajpgi.00147.2006 [Abstract] [Full Text] [PDF]  

Bart C. De Jonghe, Andras Hajnal, and Mihai Covasa

Decreased gastric mechanodetection, but preserved gastric emptying, in CCK-1 receptor-deficient OLETF rats
Am J Physiol Gastrointest Liver Physiol 291: G640-G649, 2006. First published May 25, 2006; doi:10.1152/ajpgi.00109.2006 [Abstract] [Full Text] [PDF]  

Onesmo B. Balemba, Thomas J. Heppner, Adrian D. Bonev, Mark T. Nelson, and Gary M. Mawe

Calcium waves in intact guinea pig gallbladder smooth muscle cells
Am J Physiol Gastrointest Liver Physiol 291: G717-G727, 2006. First published May 18, 2006; doi:10.1152/ajpgi.00035.2006 [Abstract] [Full Text] [PDF] [Supplemental Movies]  

CORRIGENDUM:

Corrigendum
Am J Physiol Gastrointest Liver Physiol 291: G751-G751, 2006; doi:10.1152/ajpgi.zh3-4575-corr.2006 [Full Text] [PDF]  

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