THEMES:

Arthur D. Conigrave and Edward M. Brown

Taste Receptors in the Gastrointestinal Tract II. L-Amino acid sensing by calcium-sensing receptors: implications for GI physiology
Am J Physiol Gastrointest Liver Physiol 291: G753-G761, 2006; doi:10.1152/ajpgi.00189.2006 [Abstract] [Full Text] [PDF]  

Renu N. Jain and Linda C. Samuelson

Differentiation of the Gastric Mucosa II. Role of gastrin in gastric epithelial cell proliferation and maturation
Am J Physiol Gastrointest Liver Physiol 291: G762-G765, 2006; doi:10.1152/ajpgi.00172.2006 [Abstract] [Full Text] [PDF]  

INVITED REVIEW:

G. Lamprecht and U. Seidler

The emerging role of PDZ adapter proteins for regulation of intestinal ion transport
Am J Physiol Gastrointest Liver Physiol 291: G766-G777, 2006. First published June 22, 2006; doi:10.1152/ajpgi.00135.2006 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Yasmin Nasser, Ester Fernandez, Catherine M. Keenan, Winnie Ho, Lorraine D. Oland, Lee Anne Tibbles, Michael Schemann, Wallace K. MacNaughton, Anne Rühl, and Keith A. Sharkey

Role of enteric glia in intestinal physiology: effects of the gliotoxin fluorocitrate on motor and secretory function
Am J Physiol Gastrointest Liver Physiol 291: G912-G927, 2006. First published June 22, 2006; doi:10.1152/ajpgi.00067.2006 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

W. I. Khan, Y. Motomura, H. Wang, R. T. El-Sharkawy, E. F. Verdu, M. Verma-Gandhu, B. J. Rollins, and S. M. Collins

Critical role of MCP-1 in the pathogenesis of experimental colitis in the context of immune and enterochromaffin cells
Am J Physiol Gastrointest Liver Physiol 291: G803-G811, 2006. First published May 25, 2006; doi:10.1152/ajpgi.00069.2006 [Abstract] [Full Text] [PDF]  

Mantej S. Bharhani, Rajka Borojevic, Shibesh Basak, Edwin Ho, Pengfei Zhou, and Kenneth Croitoru

IL-10 protects mouse intestinal epithelial cells from Fas-induced apoptosis via modulating Fas expression and altering caspase-8 and FLIP expression
Am J Physiol Gastrointest Liver Physiol 291: G820-G829, 2006; doi:10.1152/ajpgi.00438.2005 [Abstract] [Full Text] [PDF]  

Werner Hartwig, Martina Klafs, Michael Kirschfink, Thilo Hackert, Lutz Schneider, Martha-Maria Gebhard, Markus W. Büchler, and Jens Werner

Interaction of complement and leukocytes in severe acute pancreatitis: potential for therapeutic intervention
Am J Physiol Gastrointest Liver Physiol 291: G844-G850, 2006; doi:10.1152/ajpgi.00016.2006 [Abstract] [Full Text] [PDF]  

Courtney C. Kurtz, Susanne L. Lindell, Martin J. Mangino, and Hannah V. Carey

Hibernation confers resistance to intestinal ischemia-reperfusion injury
Am J Physiol Gastrointest Liver Physiol 291: G895-G901, 2006. First published June 1, 2006; doi:10.1152/ajpgi.00155.2006 [Abstract] [Full Text] [PDF]  

Guo-Du Wang, Xi-Yu Wang, Hong-Zhen Hu, Xiu-Cai Fang, Sumei Liu, Na Gao, and Yun Xia

Platelet-activating factor in the enteric nervous system of the guinea pig small intestine
Am J Physiol Gastrointest Liver Physiol 291: G928-G937, 2006; doi:10.1152/ajpgi.00153.2006 [Abstract] [Full Text] [PDF]  

Anneke Rijnierse, Andries S. Koster, Frans P. Nijkamp, and Aletta D. Kraneveld

TNF- is crucial for the development of mast cell-dependent colitis in mice
Am J Physiol Gastrointest Liver Physiol 291: G969-G976, 2006. First published June 22, 2006; doi:10.1152/ajpgi.00146.2006 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Nora Rozengurt, S. Vincent Wu, Monica C. Chen, Carlos Huang, Catia Sternini, and Enrique Rozengurt

Colocalization of the -subunit of gustducin with PYY and GLP-1 in L cells of human colon
Am J Physiol Gastrointest Liver Physiol 291: G792-G802, 2006. First published May 25, 2006; doi:10.1152/ajpgi.00074.2006 [Abstract] [Full Text] [PDF]  

Chirag A. Patel and Satish Rattan

Spontaneously tonic smooth muscle has characteristically higher levels of RhoA/ROK compared with the phasic smooth muscle
Am J Physiol Gastrointest Liver Physiol 291: G830-G837, 2006. First published June 8, 2006; doi:10.1152/ajpgi.00130.2006 [Abstract] [Full Text] [PDF]  

P. Kirchhoff, K. Andersson, T. Socrates, S. Sidani, O. Kosiek, and J. P. Geibel

Characteristics of the K⁺-competitive H⁺,K⁺-ATPase inhibitor AZD0865 in isolated rat gastric glands
Am J Physiol Gastrointest Liver Physiol 291: G838-G843, 2006. First published June 22, 2006; doi:10.1152/ajpgi.00120.2006 [Abstract] [Full Text] [PDF]  

Jin Shimakura, Tomohiro Terada, Hirofumi Saito, Toshiya Katsura, and Ken-ichi Inui

Induction of intestinal peptide transporter 1 expression during fasting is mediated via peroxisome proliferator-activated receptor
Am J Physiol Gastrointest Liver Physiol 291: G851-G856, 2006. First published June 1, 2006; doi:10.1152/ajpgi.00171.2006 [Abstract] [Full Text] [PDF]  

Adam J. Moeser, Prashant K. Nighot, Kathleen A. Ryan, Jenna G. Wooten, and Anthony T. Blikslager

Prostaglandin-mediated inhibition of Na⁺/H⁺ exchanger isoform 2 stimulates recovery of barrier function in ischemia-injured intestine
Am J Physiol Gastrointest Liver Physiol 291: G885-G894, 2006. First published March 30, 2006; doi:10.1152/ajpgi.00380.2005 [Abstract] [Full Text] [PDF]  

Jessica A. Clark, Sarah M. Doelle, Melissa D. Halpern, Tara A. Saunders, Hana Holubec, Katerina Dvorak, Scott A. Boitano, and Bohuslav Dvorak

Intestinal barrier failure during experimental necrotizing enterocolitis: protective effect of EGF treatment
Am J Physiol Gastrointest Liver Physiol 291: G938-G949, 2006. First published June 22, 2006; doi:10.1152/ajpgi.00090.2006 [Abstract] [Full Text] [PDF]  

Kim Hodges, Ravinder Gill, K. Ramaswamy, Pradeep K. Dudeja, and Gail Hecht

Rapid activation of Na⁺/H⁺ exchange by EPEC is PKC mediated
Am J Physiol Gastrointest Liver Physiol 291: G959-G968, 2006. First published June 15, 2006; doi:10.1152/ajpgi.00274.2005 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

M. Kidd, I. M. Modlin, G. N. Eick, and M. C. Champaneria

Isolation, functional characterization, and transcriptome of Mastomys ileal enterochromaffin cells
Am J Physiol Gastrointest Liver Physiol 291: G778-G791, 2006. First published February 2, 2006; doi:10.1152/ajpgi.00552.2005 [Abstract] [Full Text] [PDF]  

Koji Fukushima, Yoshiyuki Ueno, Jun Inoue, Noriatsu Kanno, and Tooru Shimosegawa

Filopodia formation via a specific Eph family member and PI3K in immortalized cholangiocytes
Am J Physiol Gastrointest Liver Physiol 291: G812-G819, 2006. First published June 15, 2006; doi:10.1152/ajpgi.00250.2005 [Abstract] [Full Text] [PDF]  

Shannon M. Bailey, Gloria Robinson, Anita Pinner, Laura Chamlee, Elena Ulasova, Melissa Pompilius, Grier P. Page, David Chhieng, Nirag Jhala, Aimee Landar, Kusum K. Kharbanda, Scott Ballinger, and Victor Darley-Usmar

S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver
Am J Physiol Gastrointest Liver Physiol 291: G857-G867, 2006. First published July 6, 2006; doi:10.1152/ajpgi.00044.2006 [Abstract] [Full Text] [PDF]  

M. L. Harris, A. R. Hobson, S. Hamdy, D. G. Thompson, L. M. Akkermans, and Q. Aziz

Neurophysiological evaluation of healthy human anorectal sensation
Am J Physiol Gastrointest Liver Physiol 291: G950-G958, 2006. First published May 11, 2006; doi:10.1152/ajpgi.00010.2006 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Ciprian Sandu, Ferruh Artunc, Monica Palmada, Rexhep Rexhepaj, Florian Grahammer, Azeemudeen Hussain, Chris Yun, Dario R. Alessi, and Florian Lang

Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse
Am J Physiol Gastrointest Liver Physiol 291: G868-G876, 2006. First published July 6, 2006; doi:10.1152/ajpgi.00023.2006 [Abstract] [Full Text] [PDF]  

Pau Sancho-Bru, Ramón Bataller, Jordi Colmenero, Xavier Gasull, Montserrat Moreno, Vicente Arroyo, David A. Brenner, and Pere Ginès

Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells
Am J Physiol Gastrointest Liver Physiol 291: G877-G884, 2006. First published June 15, 2006; doi:10.1152/ajpgi.00537.2005 [Abstract] [Full Text] [PDF]  

Liu Yang, Che-Chang Chan, Oh-Sang Kwon, Songling Liu, Jason McGhee, Stephen A. Stimpson, Lihong Z. Chen, W. Wallace Harrington, William T. Symonds, and Don C. Rockey

Regulation of peroxisome proliferator-activated receptor- in liver fibrosis
Am J Physiol Gastrointest Liver Physiol 291: G902-G911, 2006. First published June 22, 2006; doi:10.1152/ajpgi.00124.2006 [Abstract] [Full Text] [PDF]  

Joaquin Benitez-Rajal, Maria-Jose Lorite, Alastair D. Burt, Christopher P. Day, and Michael G. Thompson

Phospholipase D and extracellular signal-regulated kinase in hepatic stellate cells: effects of platelet-derived growth factor and extracellular nucleotides
Am J Physiol Gastrointest Liver Physiol 291: G977-G986, 2006; doi:10.1152/ajpgi.00041.2006 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Klaus Bielefeldt, Fang Zhong, H. Richard Koerber, and Brian M. Davis

Phenotypic characterization of gastric sensory neurons in mice
Am J Physiol Gastrointest Liver Physiol 291: G987-G997, 2006. First published May 25, 2006; doi:10.1152/ajpgi.00080.2006 [Abstract] [Full Text] [PDF]  

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