TRANSLATIONAL PHYSIOLOGY:

Jamilur R. Talukder, Ramesh Kekuda, Prosenjit Saha, and Uma Sundaram

Mechanism of leukotriene D₄ inhibition of Na-alanine cotransport in intestinal epithelial cells
Am J Physiol Gastrointest Liver Physiol 295: G1-G6, 2008. First published April 24, 2008; doi:10.1152/ajpgi.00498.2007 [Abstract] [Full Text] [PDF]  

Jamilur R. Talukder, Ramesh Kekuda, Prosenjit Saha, Subha Arthur, and Uma Sundaram

Identification and characterization of rabbit small intestinal villus cell brush border membrane Na-glutamine cotransporter
Am J Physiol Gastrointest Liver Physiol 295: G7-G15, 2008. First published April 24, 2008; doi:10.1152/ajpgi.00606.2007 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Catherine S. Chew, Xunsheng Chen, Roni J. Bollag, Carlos Isales, Ke Hong Ding, and Han Zhang

Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion
Am J Physiol Gastrointest Liver Physiol 295: G37-G44, 2008. First published May 15, 2008; doi:10.1152/ajpgi.90247.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Emir Q. Haxhija, Hua Yang, Ariel U. Spencer, Hiroyuki Koga, Xiaoyi Sun, and Daniel H. Teitelbaum

Modulation of mouse intestinal epithelial cell turnover in the absence of angiotensin converting enzyme
Am J Physiol Gastrointest Liver Physiol 295: G88-G98, 2008. First published May 15, 2008; doi:10.1152/ajpgi.00589.2007 [Abstract] [Full Text] [PDF]  

Yana Zavros, Melissa A. Orr, Chang Xiao, and Danuta H. Malinowska

Sonic hedgehog is associated with H⁺-K⁺-ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation
Am J Physiol Gastrointest Liver Physiol 295: G99-G111, 2008. First published May 15, 2008; doi:10.1152/ajpgi.00389.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

INFLAMMATION/IMMUNITY/MEDIATORS:

Daniel Laubitz, Claire B. Larmonier, Aiping Bai, Monica T. Midura-Kiela, Maciej A. Lipko, Robert D. Thurston, Pawel R. Kiela, and Fayez K. Ghishan

Colonic gene expression profile in NHE3-deficient mice: evidence for spontaneous distal colitis
Am J Physiol Gastrointest Liver Physiol 295: G63-G77, 2008. First published May 8, 2008; doi:10.1152/ajpgi.90207.2008 [Abstract] [Full Text] [PDF]  

Satoshi Egawa, Hideki Iijima, Shinichiro Shinzaki, Sachiko Nakajima, Jun Wang, Jumpei Kondo, Shuji Ishii, Toshiyuki Yoshio, Takanobu Irie, Tsutomu Nishida, Yoshimi Kakiuchi, Masakazu Yasumaru, Harumasa Yoshihara, Tatsuya Kanto, Masahiko Tsujii, Shingo Tsuji, and Norio Hayashi

Upregulation of GRAIL is associated with remission of ulcerative colitis
Am J Physiol Gastrointest Liver Physiol 295: G163-G169, 2008. First published May 8, 2008; doi:10.1152/ajpgi.90242.2008 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Dharmaraj Chinnappan, Xiangping Qu, Dongmei Xiao, Anita Ratnasari, and H. Christian Weber

Human gastrin-releasing peptide receptor gene regulation requires transcription factor binding at two distinct CRE sites
Am J Physiol Gastrointest Liver Physiol 295: G153-G162, 2008. First published May 15, 2008; doi:10.1152/ajpgi.00036.2008 [Abstract] [Full Text] [PDF]  

Huibin Yang, Cheong J. Lee, Lizhi Zhang, Maria Dolors Sans, and Diane M. Simeone

Regulation of transforming growth factor β-induced responses by protein kinase A in pancreatic acinar cells
Am J Physiol Gastrointest Liver Physiol 295: G170-G178, 2008. First published May 8, 2008; doi:10.1152/ajpgi.00492.2007 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

Marnie Duncan, Abdeslam Mouihate, Ken Mackie, Catherine M. Keenan, Nancy E. Buckley, Joseph S. Davison, Kamala D. Patel, Quentin J. Pittman, and Keith A. Sharkey

Cannabinoid CB₂ receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats
Am J Physiol Gastrointest Liver Physiol 295: G78-G87, 2008. First published May 15, 2008; doi:10.1152/ajpgi.90285.2008 [Abstract] [Full Text] [PDF]  

Xuefei Li, Ahmad Azlina, Mileva Ratko Karabasil, Nunuk Purwanti, Takahiro Hasegawa, Chenjuan Yao, Tetsuya Akamatsu, and Kazuo Hosoi

Degradation of submandibular gland AQP5 by parasympathetic denervation of chorda tympani and its recovery by cevimeline, an M3 muscarinic receptor agonist
Am J Physiol Gastrointest Liver Physiol 295: G112-G123, 2008. First published May 1, 2008; doi:10.1152/ajpgi.00359.2007 [Abstract] [Full Text] [PDF]  

Xuan-Zheng Shi and Sushil K. Sarna

Gene therapy of Ca_v1.2 channel with VIP and VIP receptor agonists and antagonists: a novel approach to designing promotility and antimotility agents
Am J Physiol Gastrointest Liver Physiol 295: G187-G196, 2008. First published May 8, 2008; doi:10.1152/ajpgi.00047.2008 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Mubeen Jafri, Bryan Donnelly, Steven Allen, Alex Bondoc, Monica McNeal, Paul D. Rennert, Paul H. Weinreb, Richard Ward, and Greg Tiao

Cholangiocyte expression of ₂β₁-integrin confers susceptibility to rotavirus-induced experimental biliary atresia
Am J Physiol Gastrointest Liver Physiol 295: G16-G26, 2008. First published April 24, 2008; doi:10.1152/ajpgi.00442.2007 [Abstract] [Full Text] [PDF]  

Michael Sørensen, Ole Lajord Munk, Frank Viborg Mortensen, Aage Kristian Olsen, Dirk Bender, Ludvik Bass, and Susanne Keiding

Hepatic uptake and metabolism of galactose can be quantified in vivo by 2-[¹⁸F]fluoro-2-deoxygalactose positron emission tomography
Am J Physiol Gastrointest Liver Physiol 295: G27-G36, 2008. First published May 15, 2008; doi:10.1152/ajpgi.00004.2008 [Abstract] [Full Text] [PDF]  

Bin Hu and Lisa M. Colletti

Stem cell factor and c-kit are involved in hepatic recovery after acetaminophen-induced liver injury in mice
Am J Physiol Gastrointest Liver Physiol 295: G45-G53, 2008. First published May 8, 2008; doi:10.1152/ajpgi.00024.2008 [Abstract] [Full Text] [PDF]  

Maria J. Monte, Ruben Rosales, Rocio I. R. Macias, Valeria Iannota, Almudena Martinez-Fernandez, Marta R. Romero, Alan F. Hofmann, and Jose J. G. Marin

Cytosol-nucleus traffic and colocalization with FXR of conjugated bile acids in rat hepatocytes
Am J Physiol Gastrointest Liver Physiol 295: G54-G62, 2008. First published May 8, 2008; doi:10.1152/ajpgi.00592.2007 [Abstract] [Full Text] [PDF]  

Shannon Glaser, Sharon DeMorrow, Heather Francis, Yoshiyuki Ueno, Eugenio Gaudio, Shelley Vaculin, Julie Venter, Antonio Franchitto, Paolo Onori, Bradley Vaculin, Marco Marzioni, Candace Wise, Metaneeya Pilanthananond, Jennifer Savage, Lisa Pierce, Romina Mancinelli, and Gianfranco Alpini

Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms
Am J Physiol Gastrointest Liver Physiol 295: G124-G136, 2008. First published May 29, 2008; doi:10.1152/ajpgi.00536.2007 [Abstract] [Full Text] [PDF]  

Victoria C. Cogger, Irwin M. Arias, Alessandra Warren, Aisling C. McMahon, Debra L. Kiss, Vicky M. Avery, and David G. Le Couteur

The response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells
Am J Physiol Gastrointest Liver Physiol 295: G137-G145, 2008. First published May 22, 2008; doi:10.1152/ajpgi.00069.2008 [Abstract] [Full Text] [PDF] [Supplemental Video]  

Hoe Suk Kim, Patricia A. Loughran, Jayashree Rao, Timothy R. Billiar, and Brian S. Zuckerbraun

Carbon monoxide activates NF-B via ROS generation and Akt pathways to protect against cell death of hepatocytes
Am J Physiol Gastrointest Liver Physiol 295: G146-G152, 2008. First published May 22, 2008; doi:10.1152/ajpgi.00105.2007 [Abstract] [Full Text] [PDF]  

Nazzareno Ballatori, Fang Fang, Whitney V. Christian, Na Li, and Christine L. Hammond

Ost-Ostβ is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver
Am J Physiol Gastrointest Liver Physiol 295: G179-G186, 2008. First published May 22, 2008; doi:10.1152/ajpgi.90319.2008 [Abstract] [Full Text] [PDF]  

Alexander Zipprich, Mauricio R. Loureiro-Silva, Irita D'Silva, and Roberto J. Groszmann

The role of hepatic arterial flow on portal venous and hepatic venous wedged pressure in the isolated perfused CCl₄-cirrhotic liver
Am J Physiol Gastrointest Liver Physiol 295: G197-G202, 2008. First published May 22, 2008; doi:10.1152/ajpgi.00190.2007 [Abstract] [Full Text] [PDF]  

Astrid E. van der Velde, Carlos L. J. Vrins, Karin van den Oever, Ingar Seemann, Ronald P. J. Oude Elferink, Miranda van Eck, Folkert Kuipers, and Albert K. Groen

Regulation of direct transintestinal cholesterol excretion in mice
Am J Physiol Gastrointest Liver Physiol 295: G203-G208, 2008. First published May 29, 2008; doi:10.1152/ajpgi.90231.2008 [Abstract] [Full Text] [PDF]  

LETTER TO THE EDITOR:

H. C. McKirdy

Gallbladder nitric oxide
Am J Physiol Gastrointest Liver Physiol 295: G209-G209, 2008; doi:10.1152/ajpgi.90305.2008 [Full Text] [PDF]  

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