THEMES:

George Kunos and Douglas Osei-Hyiaman

Endocannabinoids and Liver Disease. IV. Endocannabinoid involvement in obesity and hepatic steatosis
Am J Physiol Gastrointest Liver Physiol 294: G1101-G1104, 2008. First published February 21, 2008; doi:10.1152/ajpgi.00057.2008 [Abstract] [Full Text] [PDF]  

Yana Zavros

The Adventures of Sonic Hedgehog in Development and Repair. IV. Sonic hedgehog processing, secretion, and function in the stomach
Am J Physiol Gastrointest Liver Physiol 294: G1105-G1108, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00031.2008 [Abstract] [Full Text] [PDF]  

HISTORICAL PERSPECTIVES:

Paul H. Guth and Jonathan D. Kaunitz

Personal reminiscences about Morton Grossman and the founding of the Center for Ulcer Research and Education (CURE)
Am J Physiol Gastrointest Liver Physiol 294: G1109-G1113, 2008. First published March 20, 2008; doi:10.1152/ajpgi.00594.2007 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

V. K. Viswanathan, Andrew Weflen, Athanasia Koutsouris, Jennifer L. Roxas, and Gail Hecht

Enteropathogenic E. coli-induced barrier function alteration is not a consequence of host cell apoptosis
Am J Physiol Gastrointest Liver Physiol 294: G1165-G1170, 2008. First published March 20, 2008; doi:10.1152/ajpgi.00596.2007 [Abstract] [Full Text] [PDF]  

Heleen M. de Vogel-van den Bosch, Nicole J. W. de Wit, Guido J. E. J. Hooiveld, Hanneke Vermeulen, Jelske N. van der Veen, Sander M. Houten, Folkert Kuipers, Michael Müller, and Roelof van der Meer

A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine
Am J Physiol Gastrointest Liver Physiol 294: G1171-G1180, 2008. First published March 20, 2008; doi:10.1152/ajpgi.00360.2007 [Abstract] [Full Text] [PDF] [Supplemental Table]  

Jing Lu, Michael S. Caplan, Dan Li, and Tamas Jilling

Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells
Am J Physiol Gastrointest Liver Physiol 294: G1181-G1190, 2008. First published March 20, 2008; doi:10.1152/ajpgi.00343.2007 [Abstract] [Full Text] [PDF] [Supplemental Videos]  

Erika C. Claud, Jing Lu, Xue Qing Wang, Mark Abe, Elaine O. Petrof, Jun Sun, Deborah J. Nelson, Jeremy Marks, and Tamas Jilling

Platelet-activating factor-induced chloride channel activation is associated with intracellular acidosis and apoptosis of intestinal epithelial cells
Am J Physiol Gastrointest Liver Physiol 294: G1191-G1200, 2008. First published March 13, 2008; doi:10.1152/ajpgi.00318.2007 [Abstract] [Full Text] [PDF]  

Gopalan Natarajan, Satish Ramalingam, Ilangovan Ramachandran, Randal May, Lurdes Queimado, Courtney W. Houchen, and Shrikant Anant

CUGBP2 downregulation by prostaglandin E₂ protects colon cancer cells from radiation-induced mitotic catastrophe
Am J Physiol Gastrointest Liver Physiol 294: G1235-G1244, 2008. First published March 6, 2008; doi:10.1152/ajpgi.00037.2008 [Abstract] [Full Text] [PDF]  

Alice Miles, Evaggelia Liaskou, Bertus Eksteen, Patricia F. Lalor, and David H. Adams

CCL25 and CCL28 promote ₄β₇-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow
Am J Physiol Gastrointest Liver Physiol 294: G1257-G1267, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00266.2007 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

Emanuela Mazzon and Salvatore Cuzzocrea

Role of TNF- in ileum tight junction alteration in mouse model of restraint stress
Am J Physiol Gastrointest Liver Physiol 294: G1268-G1280, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00014.2008 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Bolin Qin, Richard A. Anderson, and Khosrow Adeli

Tumor necrosis factor- directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling
Am J Physiol Gastrointest Liver Physiol 294: G1120-G1129, 2008. First published March 27, 2008; doi:10.1152/ajpgi.00407.2007 [Abstract] [Full Text] [PDF]  

Wendell J. Lu, Qing Yang, William Sun, Stephen C. Woods, David D'Alessio, and Patrick Tso

Using the lymph fistula rat model to study the potentiation of GIP secretion by the ingestion of fat and glucose
Am J Physiol Gastrointest Liver Physiol 294: G1130-G1138, 2008. First published March 27, 2008; doi:10.1152/ajpgi.00400.2007 [Abstract] [Full Text] [PDF]  

Martin Wagner, Stefan Koschnick, Sven Beilke, Melanie Frey, Guido Adler, and Roland M. Schmid

Selective expansion of the β-cell compartment in the pancreas of keratinocyte growth factor transgenic mice
Am J Physiol Gastrointest Liver Physiol 294: G1139-G1147, 2008. First published March 27, 2008; doi:10.1152/ajpgi.00338.2007 [Abstract] [Full Text] [PDF]  

Stephen J. Crozier, Maria Dolors Sans, Charles H. Lang, Louis G. D'Alecy, Stephen A. Ernst, and John A. Williams

CCK-induced pancreatic growth is not limited by mitogenic capacity in mice
Am J Physiol Gastrointest Liver Physiol 294: G1148-G1157, 2008. First published March 20, 2008; doi:10.1152/ajpgi.00426.2007 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

April B. M. Grudell, Michael Camilleri, Kim L. Jensen, Amy E. Foxx-Orenstein, Duane D. Burton, Michael D. Ryks, Kari L. Baxter, Donna S. Cox, George E. Dukes, Dennis L. Kelleher, and Alan R. Zinsmeister

Dose-response effect of a β₃-adrenergic receptor agonist, solabegron, on gastrointestinal transit, bowel function, and somatostatin levels in health
Am J Physiol Gastrointest Liver Physiol 294: G1114-G1119, 2008. First published March 27, 2008; doi:10.1152/ajpgi.00051.2008 [Abstract] [Full Text] [PDF]  

Shi-Yi Zhou, Yuan-Xu Lu, and Chung Owyang

Gastric relaxation induced by hyperglycemia is mediated by vagal afferent pathways in the rat
Am J Physiol Gastrointest Liver Physiol 294: G1158-G1164, 2008. First published March 20, 2008; doi:10.1152/ajpgi.00067.2008 [Abstract] [Full Text] [PDF]  

Shi-Yi Zhou, Yuan-Xu Lu, HongRen Yao, and Chung Owyang

Spatial organization of neurons in the dorsal motor nucleus of the vagus synapsing with intragastric cholinergic and nitric oxide/VIP neurons in the rat
Am J Physiol Gastrointest Liver Physiol 294: G1201-G1209, 2008; doi:10.1152/ajpgi.00309.2006 [Abstract] [Full Text] [PDF]  

Koji Ataka, Akio Inui, Akihiro Asakawa, Ikuo Kato, and Mineko Fujimiya

Obestatin inhibits motor activity in the antrum and duodenum in the fed state of conscious rats
Am J Physiol Gastrointest Liver Physiol 294: G1210-G1218, 2008. First published March 6, 2008; doi:10.1152/ajpgi.00549.2007 [Abstract] [Full Text] [PDF]  

D. P. Poole, S. Amadesi, E. Rozengurt, M. Thacker, N. W. Bunnett, and J. B. Furness

Stimulation of the neurokinin 3 receptor activates protein kinase C and protein kinase D in enteric neurons
Am J Physiol Gastrointest Liver Physiol 294: G1245-G1256, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00521.2007 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Sang Ho Lee, Cathy Culberson, Katarzyna Korneszczuk, and Mark G. Clemens

Differential mechanisms of hepatic vascular dysregulation with mild vs. moderate ischemia-reperfusion
Am J Physiol Gastrointest Liver Physiol 294: G1219-G1226, 2008. First published March 6, 2008; doi:10.1152/ajpgi.00527.2007 [Abstract] [Full Text] [PDF]  

Claudia von Montfort, Juliane I. Beier, Luping Guo, J. Phillip Kaiser, and Gavin E. Arteel

Contribution of the sympathetic hormone epinephrine to the sensitizing effect of ethanol on LPS-induced liver damage in mice
Am J Physiol Gastrointest Liver Physiol 294: G1227-G1234, 2008. First published March 6, 2008; doi:10.1152/ajpgi.00050.2008 [Abstract] [Full Text] [PDF]  

Dario Greco, Anna Kotronen, Jukka Westerbacka, Oscar Puig, Perttu Arkkila, Tuula Kiviluoto, Saara Laitinen, Maria Kolak, Rachel M. Fisher, Anders Hamsten, Petri Auvinen, and Hannele Yki-Järvinen

Gene expression in human NAFLD
Am J Physiol Gastrointest Liver Physiol 294: G1281-G1287, 2008. First published April 3, 2008; doi:10.1152/ajpgi.00074.2008 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

REPORTS:

Walter E. B. Sipe, Stuart M. Brierley, Christopher M. Martin, Benjamin D. Phillis, Francisco Bautista Cruz, Eileen F. Grady, Wolfgang Liedtke, David M. Cohen, Stephen Vanner, L. Ashley Blackshaw, and Nigel W. Bunnett

Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia
Am J Physiol Gastrointest Liver Physiol 294: G1288-G1298, 2008. First published March 6, 2008; doi:10.1152/ajpgi.00002.2008 [Abstract] [Full Text] [PDF]  

CORRIGENDUM:

Corrigendum for Sarna, Am J Physiol Gastrointest Liver Physiol 294(2): G372–G390, 2008.
Am J Physiol Gastrointest Liver Physiol 294: G1299-G1299, 2008; doi:10.1152/ajpgi.zh3-5101-corr.2008 [Full Text] [PDF]  

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