Table 1.

Changes in mouse colon microRNA expression induced by AOM/DSS treatment

AOM/DSS d65 vs. PBS d65AOM/DSS d65 vs. AOM/DSS d15AOM/DSS d65 vs. AOM/DSS d50
miRNARatioP valueRatioP valueRatioP value
MMU-LET-7E0.880.0541.770.04651.121
MMU-LET-7I*10.03350.720.03420.590.0399
MMU-MIR-15A1.380.0542.410.04651.450.0399
MMU-MIR-171.310.03351.520.7511.780.0399
MMU-MIR-18A1.840.0541.250.87012.330.0399
MMU-MIR-19A1.80.03351.820.04652.360.0399
MMU-MIR-24-2*0.60.03351.860.09851.170.8493
MMU-MIR-29C0.760.23922.570.04650.890.0985
MMU-MIR-34A1.040.61793.80.03421.570.0985
MMU-MIR-961.220.50144.260.03422.110.0399
MMU-MIR-99A1.112.850.03421.620.2014
MMU-MIR-99B0.940.50142.270.03421.350.2014
MMU-MIR-101A0.660.3190.40.03420.280.0568
MMU-MIR-106A1.470.3192.490.03421.780.0568
MMU-MIR-1240.880.11960.540.04650.480.1446
MMU-MIR-125A-3P2.940.03351.860.20531.710.0797
MMU-MIR-139-5P1.0512.420.03421.340.4877
MMU-MIR-140*1.870.03352.280.04651.870.0399
MMU-MIR-142-5P5.140.03353.880.03422.640.0399
MMU-MIR-146A2.560.03354.510.03422.190.0399
MMU-MIR-146B4.380.03352.050.03422.650.0399
MMU-MIR-148A0.980.39824.10.03421.430.0985
MMU-MIR-1503.980.03352.690.06982.830.0568
MMU-MIR-151-5P1.0812.60.03421.720.1446
MMU-MIR-1521.020.87012.660.03421.620.2014
MMU-MIR-1821.130.61793.440.03421.90.0399
MMU-MIR-1831.780.03351.560.29121.590.0399
MMU-MIR-1930.620.03351.70.20530.910.4877
MMU-MIR-193B0.750.3192.720.03420.960.605
MMU-MIR-196B1.20.76282.610.04651.630.2014
MMU-MIR-199A-5P1.20.08271.80.04651.150.2014
MMU-MIR-2031.960.08272.670.06982.580.0399
MMU-MIR-2051.280.11964.260.03421.740.0399
MMU-MIR-2122.10.03351.610.29121.880.0399
MMU-MIR-2142.490.03351.80.14671.760.0399
MMU-MIR-216A0.830.50140.40.03420.510.0399
MMU-MIR-2233.970.03351.650.29122.530.0399
MMU-MIR-292-3P0.710.03350.580.04650.60.0797
MMU-MIR-302B*0.580.11960.550.03420.620.0985
MMU-MIR-322/4240.610.23920.550.03420.490.0568
MMU-MIR-328-5P3.360.11961.650.37972.170.0399
MMU-MIR-337-3P0.680.3190.480.03420.660.0399
MMU-MIR-342-3P2.640.03352.440.04652.090.0568
MMU-MIR-3611.380.0542.050.03421.810.0568
MMU-MIR-3750.980.3192.380.04651.260.1446
MMU-MIR-376C0.560.50140.420.03420.620.0985
MMU-MIR-384-5P0.520.11960.530.03420.640.0985
MMU-MIR-421-3P0.860.23920.510.03420.610.0399
MMU-MIR-4251.320.16892.450.09852.080.0399
MMU-MIR-4511.430.16893.690.03421.410.605
MMU-MIR-4942.440.03351.130.7512.450.0399
MMU-MIR-4971.270.16892.180.03421.280.2774
MMU-MIR-5030.850.16890.440.04650.530.0985
MMU-MIR-574-3P0.630.0540.520.04650.420.0399
MMU-MIR-654-3P0.650.11960.440.03420.510.0568
MMU-MIR-675-3P0.730.03350.430.03420.440.0399
MMU-MIR-6790.720.11960.550.04650.570.0985
MMU-MIR-6852.070.16892.150.03422.460.0399
MMU-MIR-6860.720.08270.460.04650.50.0797
MMU-MIR-7053.340.03352.530.14672.140.0399
MMU-MIR-7140.760.03350.570.03420.630.1446
MMU-MIR-7623.130.08272.460.06985.080.0399
MMU-MIR-8710.70.23920.520.04650.570.0568
MMU-MIR-11940.940.23920.510.06980.40.0399
MMU-MIR-12245.480.03352.380.04651.890.0797
MMU-MIR-18952.10.31920.04652.20.0399
MMU-MIR-193160.03353.610.03423.240.0399
MMU-MIR-1937A0.990.11960.90.03420.580.0399
MMU-MIR-19400.930.03350.560.04650.520.0399
MMU-MIR-19594.960.03354.360.03426.960.0399
MMU-MIR-19832.10.23922.580.14673.630.0399
  • P values were obtained by a Mann-Whitney test and corrected for multitesting by the Benjamini-Hochberg method. MicroRNA (miRNA) with P < 0.05 in at least 1 comparison, azoxymethane (AOM)/dextran sulfate sodium (DSS) day 65 (d65) vs. PBS d65, AOM/DSS d65 vs. AOM/DSS day 15 (d15), or AOM/DSS d65 vs. AOM/DSS day 50 (d50), and with at least 1.6-fold of expression variation are listed.

  • * miRNA star.