Table 3.

List of miRNAs differentially expressed in whole colons of AOM/DSS-treated mice and in human colorectal cancer

miRNAAOM/DSS Mouse ModelHuman CRCReference
let-7eupdown10
miR-17upup20, 46
miR-18aupup20, 5, 48, 46, 10
miR-19aupup5, 48, 6, 10
miR-29cupdown20
miR-34aupup5, 6, 45
down3
miR-96upup5, 6, 45, 26
miR-99bupup63
miR-101adowndown20, 56
miR-106aupup63, 57, 5, 48, 6, 10, 45
down16
miR-139-5pupdown5, 6, 45, 10, 26
miR-146aupup6, 45
miR-146bupdown56
miR-148aupup6, 45
down20
miR-150upup45, 63
down10
miR-182upup5, 6, 45
miR-183upup46
miR-203upup63, 57, 5, 10, 45
miR-205upup45, 10
miR-212upup57, 56
down10
miR-214updown6, 10
miR-223upup20, 57, 48, 45, 10, 17, 63, 39
miR-328-5Pupdown6
miR-375updown20
  • Only mouse colon miRNAs significantly modified by AOM/DSS treatment (P < 0.05, see Table 1) are considered for comparison.